SCHEMBL21138213

SCHEMBL21138213

CCCC(=O)N[C@H]1C(C)O[C@H](COC(=O)c2ccccc2O)[C@@H](O)[C@@H]1O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.37
▸ TDP1 Q9NUW8 3/20 0.37
▸ TSHR P16473 1/20 0.36
▸ CDC25B P30305 1/20 0.36
▸ GAA P10253 2/20 0.36
▸ BCHE P06276 1/20 0.36
▸ PYGB P11216 1/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ CTDSP1 Q9GZU7 1/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ SSTR1 P30872 1/20 0.35
▸ SSTR2 P30874 1/20 0.35
▸ SSTR4 P31391 1/20 0.35
▸ SSTR3 P32745 1/20 0.35
▸ SSTR5 P35346 1/20 0.35
▸ ALDH1A1 P00352 4/20 0.34
▸ SMN1; SMN2 Q16637 2/20 0.34
▸ HTT P42858 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ ADRB2 P07550 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21058343 0.91 HK1 (0.40) LMNATDP1TSHRCDC25BGAA
SCHEMBL21138776 0.90 ALDH1A1 (0.35) CDC25BGAAPYGBSSTR1SSTR2
SCHEMBL25835981 0.90 SSTR3 (0.35) GAAPYGBSSTR1SSTR2SSTR4
SCHEMBL25835057 0.81 HK1 (0.39) CDC25BGAAPYGBSSTR1SSTR2
SCHEMBL21138297 0.80 LMNA (0.35) LMNATDP1TSHRCDC25BGAA
SCHEMBL21138290 0.80 BCHE (0.42) LMNATDP1TSHRCDC25BGAA
SCHEMBL21138642 0.79 L3MBTL1 (0.45) LMNATDP1TSHRL3MBTL1KDM4E
SCHEMBL21137906 0.79 PYGB (0.44) GAAPYGBL3MBTL1ALDH1A1
SCHEMBL21137875 0.75 PYGB (0.40) GAAPYGBL3MBTL1
SCHEMBL21137914 0.75 PYGB (0.35) GAAPYGBKDM4ESSTR4SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-08-08 — — US disclosed
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN SUZHOU PHARMA TECH CO LTD (CN) 2023-07-20 — — US disclosed
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2023-02-28 — — US disclosed
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS Risen (Suzhou) Pharma Tech Co., Ltd. (CN) 2021-03-18 — — US disclosed
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF RISEN (SUZHOU) PHARMA TECH CO, LTD. (CN) 2019-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210079033-A1 GLUCOSAMINE DERIVATIVES FOR THE PREVENTION OR TREATMENT OF JOINT DISORDERS OGT, UGGT1, GLA LMNA 2632/4885TDP1 4185/4885TSHR 3413/4885
US-11718636-B2 Glucosamine derivatives for the prevention or treatment of joint disorders OGT, UGGT1, GLA LMNA 2632/4885TDP1 4185/4885TSHR 3413/4885
US-20230227488-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA LMNA 2743/4885TDP1 4136/4885TSHR 2995/4885
US-20190185502-A1 GLUCOSAMINE DERIVATIVES AND PHARMACEUTICAL USES THEREOF OGT, UGGT1, GLA LMNA 2743/4885TDP1 4136/4885TSHR 2995/4885
US-11591358-B2 Glucosamine derivatives and pharmaceutical uses thereof OGT, UGGT1, GLA LMNA 2743/4885TDP1 4136/4885TSHR 2995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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