Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.41 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL346163 | 0.80 | NOTUM (0.42) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL4322903 | 0.80 | ENPP3 (0.42) | RAB9ANPC1MEN1KMT2ACASP3 | |
| SCHEMBL1154499 | 0.80 | MAPT (0.42) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL4308652 | 0.80 | RAB9A (0.40) | RAB9ANPC1MEN1KMT2ANOTUM | |
| SCHEMBL973674 | 0.78 | CYP2A6 (0.50) | RAB9ANPC1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL2407790 | 0.78 | CYP1A2 (0.51) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2590942 | 0.78 | RAB9A (0.54) | RAB9ANPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8836004 | 0.77 | ENPP3 (0.45) | RAB9ANPC1SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL9269460 | 0.77 | ESR2 (0.47) | MEN1KMT2ANOTUMMAPTALDH1A1 | |
| SCHEMBL1897908 | 0.77 | NOTUM (0.47) | RAB9ANPC1NOTUMSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 496 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255900-A1 | CYSTEINYL LEUKOTRIENE RECEPTOR LIGANDS DIRECTED TOWARD THE TREATMENT OF INFLAMMATORY AND ONCOLOGICAL DISEASES | федеральное государственное автономное образовательное учреждение высшего образования "Московский физико-технический институт (национальный исследовательский университет)" | 2022-12-08 | — | — | WO | claimed |
| CN-109071506-B | Substituted 2- (hetero) arylimidazolyl carboxamides as pest control agents | 拜耳作物科学股份公司 | 2021-03-02 | — | — | CN | claimed |
| US-10544124-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-01-28 | — | — | US | claimed |
| US-10239882-B2 | Substituted 5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine compounds as PDE2 inhibitors | DART NEUROSCIENCE (CAYMAN) LTD. (KY) | 2019-03-26 | — | — | US | claimed |
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARMACEUTICALS, INC. | 2019-03-07 | — | — | US | claimed |
| US-20190047982-A1 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-02-14 | — | — | US | claimed |
| EP-3414236-A1 | SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2018-12-19 | — | — | EP | claimed |
| US-20180282338-A1 | SUBSTITUTED 5-METHYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-AMINE COMPOUNDS AS PDE2 INHIBITORS | DART NEUROSCIENCE LLC | 2018-10-04 | — | — | US | claimed |
| EP-3215508-A1 | SUBSTITUTED 5-METHYL-[1, 2, 4]TRIAZOLO [1,5-A) PYRIMIDIN-2-AMINE COMPOUNDS AS PDE2 INHIBITORS | Dart NeuroScience (Cayman) Ltd. (KY) | 2017-09-13 | — | — | EP | claimed |
| WO-2017137338-A1 | SUBSTITUIERTED 2-(HET)ARYL-IMIDAZOLYL-CARBOXYAMIDES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-08-17 | — | — | WO | claimed |
| EP-0275821-B1 | SUBSTITUTED ALKANEDIPHOSPHONIC ACIDS | CIBA-GEIGY AG (CH) | 1992-02-26 | — | — | EP | claimed |
| US-5085686-A | Plant growth regulator | BASF AKTIENGESELLSCHAFT (DE) | 1992-02-04 | — | — | US | claimed |
| US-5071841-A | For prevention of bone reabsorption | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-12-10 | — | — | US | claimed |
| EP-0162224-B1 | CYCLOHEXENONE DERIVATIVES AND THEIR USE FOR COMBATING UNDESIRABLE VEGETATION | BASF Aktiengesellschaft (DE) | 1990-10-31 | — | — | EP | claimed |
| EP-0177913-B1 | CYCLOHEXENONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1990-01-03 | — | — | EP | claimed |
| EP-0313997-A2 | Medicine, therein contained phosphor containing 2-isoxazolidines and isoxazoles, as well as process for preparing those heterocyclic compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-05-03 | — | — | EP | claimed |
| US-4624696-A | Cyclohexenone derivatives and their use for controlling undesirable plant growth | BASF AKTIENGESELLSCHAFT (DE) | 1986-11-25 | — | — | US | claimed |
| EP-0177913-A1 | Cyclohexenone derivatives, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1986-04-16 | — | — | EP | claimed |
| US-4113938-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1978-09-12 | — | — | US | claimed |
| US-4113937-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1978-09-12 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190047982-A1 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | RAB9A 480/4885NPC1 4643/4885MEN1 3925/4885 |
| US-10239882-B2 | Substituted 5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-amine compounds as PDE2 inhibitors | PDE12, PDE2A, PDE3A | RAB9A 1415/4885NPC1 3338/4885MEN1 2189/4885 |
| US-20180282338-A1 | SUBSTITUTED 5-METHYL-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDIN-2-AMINE COMPOUNDS AS PDE2 INHIBITORS | PDE12, PDE2A, PDE3A | RAB9A 1415/4885NPC1 3338/4885MEN1 2189/4885 |
| US-20190070149-A1 | PRIMARY AMINES AND DERIVATIVES THEREOF AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | HTR5A, HTR2A, HTR1A | RAB9A 1172/4885NPC1 653/4885MEN1 3346/4885 |
| US-10544124-B2 | Substituted 2-(het)arylimidazolylcarboxyamides as pesticides | DDT, CYP4X1, CYP4Z1 | RAB9A 480/4885NPC1 4643/4885MEN1 3925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.