Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.53 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL197017 | 0.76 | LMNA (0.72) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL16051250 | 0.76 | PKM (0.44) | RAB9ASMN1; SMN2NPC1LMNACYP1A2 | |
| SCHEMBL28953186 | 0.75 | GSTP1 (0.48) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL27743534 | 0.74 | CYP1A2 (0.61) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL23483029 | 0.74 | LMNA (0.69) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL1096817 | 0.74 | LMNA (0.69) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL27367676 | 0.74 | LMNA (0.82) | RAB9ASMN1; SMN2LMNACYP1A2PTGS1 | |
| SCHEMBL339813 | 0.74 | LMNA (0.82) | RAB9ASMN1; SMN2LMNACYP1A2PTGS1 | |
| SCHEMBL8978594 | 0.74 | ENPP3 (0.58) | RAB9ASMN1; SMN2MEN1NPC1POLB | |
| SCHEMBL254671 | 0.73 | LMNA (0.88) | RAB9ASMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8841335-B2 | Pharmaceutical composition for inhibiting apoptosis of neuron or neurodegeneration | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2014-09-23 | — | — | US | disclosed |
| EP-2566475-A2 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK Biopharmaceuticals Co., Ltd. (KR) | 2013-03-13 | — | — | EP | disclosed |
| US-20130046001-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2013-02-21 | — | — | US | disclosed |
| WO-2011139079-A2 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2011-11-10 | — | — | WO | disclosed |
| US-20080045580-A1 | Novel Isoxazole Compounds Having Ppar Agonist Activity | DR REDDY'S LABORATORIES LIMITED (IN) | 2008-02-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045580-A1 | Novel Isoxazole Compounds Having Ppar Agonist Activity | PPARG, PPARA, PPARD | RAB9A 2782/4885SMN1; SMN2 4709/4885MEN1 4842/4885 |
| US-20130046001-A1 | PHARMACEUTICAL COMPOSITION FOR INHIBITING APOPTOSIS OF NEURON OR NEURODEGENERATION | BAX, NLN, CASP3 | RAB9A 2788/4885SMN1; SMN2 15/4885MEN1 4505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.