SCHEMBL21151247

SCHEMBL21151247

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4cccc5c4-c4ccccc4C54c5ccccc5Sc5ccccc54)cc3)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 2/20 0.35
ADORA2A P29274 2/20 0.35
ADORA2B P29275 2/20 0.35
ADORA1 P30542 2/20 0.35
TSHR P16473 2/20 0.35
ALOX15 P16050 1/20 0.35
GPR55 Q9Y2T6 1/20 0.35
PDK2 Q15119 4/20 0.33
POLB P06746 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPT P10636 4/20 0.33
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 2/20 0.33
HPGD P15428 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22908045 0.99 ADORA3 (0.35) ADORA3ADORA2AADORA2BADORA1TSHR
SCHEMBL22908169 0.93 ALOX15 (0.35) ADORA3ADORA2AADORA2BADORA1TSHR
SCHEMBL21151252 0.93 ALOX15 (0.35) ADORA3ADORA2AADORA2BADORA1TSHR
SCHEMBL21151976 0.93 TSHR (0.36) ADORA3ADORA2AADORA2BADORA1TSHR
SCHEMBL23965156 0.93 KDM4E (0.39) ADORA3ADORA2AADORA2BADORA1TSHR
SCHEMBL21151246 0.92 MEN1 (0.41) ADORA2AADORA1MAPTALDH1A1MEN1
SCHEMBL24844555 0.92 MEN1 (0.33) ADORA3ADORA2AADORA2BADORA1TSHR
SCHEMBL21151245 0.92 MEN1 (0.41) ADORA2AADORA1MAPTALDH1A1MEN1
SCHEMBL21477886 0.92 ALOX15 (0.34) ADORA3ADORA2AADORA2BADORA1TSHR
SCHEMBL23965371 0.92 MEN1 (0.36) ADORA3ADORA2AADORA2BADORA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244970-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
US-20240244970-A1 ORGANIC LIGHT EMITTING DIODE AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2024-07-18 US disclosed
WO-2024117762-A1 ORGANIC LIGHT EMITTING DEVICE 주식회사 엘지화학 2024-06-06 WO disclosed
US-20230006161-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2023-01-05 US disclosed
US-20210143344-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2021-05-13 US disclosed
US-20210020842-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-21 US disclosed
WO-2020022768-A1 ORGANIC LIGHT EMITTING DIODE 주식회사 엘지화학 2020-01-30 WO disclosed
WO-2020022771-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2020-01-30 WO disclosed
US-20190214571-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190214571-A1 ORGANIC LIGHT EMITTING DEVICE PPOX, ERO1A, HMOX2 ADORA3 4692/4885ADORA2A 4802/4885ADORA2B 4841/4885
US-20210020842-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, OR51E2, LOXL1 ADORA3 4367/4885ADORA2A 4182/4885ADORA2B 3971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.