SCHEMBL21152902

SCHEMBL21152902

CCC(=O)c1ccc(CNC(C)C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.46
SMN1; SMN2 Q16637 4/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
RAB9A P51151 5/20 0.45
KMT2A Q03164 4/20 0.45
MEN1 O00255 2/20 0.45
NPC1 O15118 1/20 0.45
ALDH1A1 P00352 3/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.45
ALOX15 P16050 1/20 0.45
CYP2C19 P33261 1/20 0.45
PTGS2 P35354 1/20 0.45
POLB P06746 1/20 0.44
GAA P10253 1/20 0.41
HTT P42858 1/20 0.41
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40
HDAC6 Q9UBN7 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20850576 0.81 ALDH1A1 (0.47) SMN1; SMN2RAB9AKMT2AMEN1NPC1
SCHEMBL12674550 0.81 KMT2A (0.55) MAPTSMN1; SMN2RAB9AKMT2AMEN1
SCHEMBL9911525 0.81 KMT2A (0.59) L3MBTL1KMT2AALDH1A1LMNACYP1A2
SCHEMBL19287247 0.80 MEP1B (0.52) KMT2AMEN1HDAC6PRKD1HDAC3
SCHEMBL12667380 0.80 ALDH1A1 (0.46) MAPTSMN1; SMN2RAB9AKMT2AMEN1
SCHEMBL18602021 0.79 MAPT (0.50) MAPTSMN1; SMN2L3MBTL1RAB9AKMT2A
SCHEMBL18972056 0.79 MEN1 (0.51) MAPTSMN1; SMN2RAB9AKMT2AMEN1
SCHEMBL3114984 0.79 LOXL2 (0.58) MAPTRAB9AKMT2AMEN1NPC1
SCHEMBL3271284 0.78 SIGMAR1 (0.48) SMN1; SMN2ALDH1A1LMNACYP1A2ALOX15
SCHEMBL24239461 0.77 ALDH1A1 (0.44) SMN1; SMN2RAB9AKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190209702-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2019-07-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190209702-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 MAPT 2910/4885SMN1; SMN2 3669/4885L3MBTL1 2958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.