Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14491194 | 0.80 | ALDH1A1 (0.43) | ALDH1A1BRD4HPGDNOTUMTSHR | |
| SCHEMBL9279350 | 0.80 | BRD4 (0.41) | ALDH1A1BRD4HPGDTSHRMAPK1 | |
| SCHEMBL11040309 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TSHRAKR1B1LMNACES2 | |
| SCHEMBL1043659 | 0.77 | CASP1 (0.53) | ALDH1A1CES2CES1CASP1 | |
| SCHEMBL30799810 | 0.77 | CASP1 (0.53) | ALDH1A1CES2CES1CASP1 | |
| SCHEMBL5179498 | 0.77 | ALDH1A1 (0.40) | ALDH1A1BRD4NOTUMTSHRAKR1B1 | |
| SCHEMBL1045194 | 0.77 | CASP1 (0.53) | ALDH1A1CES2CES1CASP1 | |
| SCHEMBL67881 | 0.77 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRAKR1B1LMNA | |
| SCHEMBL13170115 | 0.74 | CES2 (0.62) | HPGDLMNACES2CES1MAPK1 | |
| SCHEMBL12907075 | 0.74 | ACP3 (0.46) | ALDH1A1BRD4HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10351519-B2 | Sulfamate derivative compounds, processes for preparing them and their uses | BIO-PHARM SOLUTIONS CO., LTD. (KR) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10351519-B2 | Sulfamate derivative compounds, processes for preparing them and their uses | STS, SULT2A1, SULT1A1 | ALDH1A1 844/4885BRD4 2516/4885HPGD 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.