Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 2/20 | 0.43 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21523951 | 0.86 | SSTR4 (0.42) | SSTR4PRKCZCYP11B1CYP11B2ADRA2A | |
| SCHEMBL25541010 | 0.82 | SSTR4 (0.46) | SSTR4PRKCZSLC22A12CYP1A2CYP3A4 | |
| SCHEMBL2126064 | 0.80 | CYP2A6 (0.40) | CYP1A2CYP2D6CYP2C19KDM4EALDH1A1 | |
| SCHEMBL21018235 | 0.78 | TRPV1 (0.32) | SLC22A12 | |
| SCHEMBL803042 | 0.78 | SSTR4 (0.46) | SSTR4PRKCZCYP11B1CYP11B2ADRA2A | |
| SCHEMBL22639188 | 0.78 | CYP3A4 (0.46) | SSTR4PRKCZCYP11B1CYP11B2ADRA2A | |
| SCHEMBL24656746 | 0.76 | MAPT (0.36) | SLC22A12CYP3A4CYP17A1KDM4E | |
| SCHEMBL16240891 | 0.75 | SSTR4 (0.44) | SSTR4PRKCZCYP11B1CYP11B2ADRA2A | |
| SCHEMBL22794684 | 0.73 | LMNA (0.46) | SSTR4PRKCZSLC22A12CYP1A2CYP3A4 | |
| SCHEMBL11142241 | 0.71 | CYP11B2 (0.55) | SSTR4PRKCZCYP11B1CYP11B2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11066447-B2 | Aureobasidium derivatives and methods of synthesis | AueroGen Biosciences, Inc. (US) | 2021-07-20 | — | — | US | disclosed |
| US-20190292225-A1 | AUREOBASIDIUM DERIVATIVES AND METHODS OF SYNTHESIS | AUREOGEN BIOSCIENCES, INC. | 2019-09-26 | — | — | US | disclosed |
| US-10351572-B2 | Aryl hydrocarbon receptor antagonists and uses thereof | Magenta Therapeutics Inc. (US) | 2019-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190292225-A1 | AUREOBASIDIUM DERIVATIVES AND METHODS OF SYNTHESIS | ERG28, FDPS, AAAS | SSTR4 3418/4885PRKCZ 3365/4885CYP11B1 296/4885 |
| US-11066447-B2 | Aureobasidium derivatives and methods of synthesis | ERG28, FDPS, AAAS | SSTR4 3418/4885PRKCZ 3365/4885CYP11B1 296/4885 |
| US-10351572-B2 | Aryl hydrocarbon receptor antagonists and uses thereof | AHR, ARNT, AIPL1 | SSTR4 1646/4885PRKCZ 3074/4885CYP11B1 1022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.