Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 10/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 1.00 |
| ▸ | LMNA | P02545 | 5/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | GFER | P55789 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | NPC1 | O15118 | 8/20 | 0.65 |
| ▸ | RAB9A | P51151 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.65 |
| ▸ | HTT | P42858 | 5/20 | 0.65 |
| ▸ | GAA | P10253 | 3/20 | 0.65 |
| ▸ | AXL | P30530 | 1/20 | 0.61 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22833881 | 0.86 | MAPT (0.75) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29379319 | 0.86 | MAPT (0.75) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL15617128 | 0.82 | MAPT (0.70) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL17252042 | 0.82 | MAPT (0.70) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28878446 | 0.79 | MAPT (0.66) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL29974715 | 0.79 | MAPT (0.66) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6641942 | 0.79 | DYRK1A (0.74) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL22468022 | 0.79 | PDPK1 (0.65) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2115626 | 0.79 | NPC1 (0.65) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL2116067 | 0.79 | MEN1 (1.00) | MAPTKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160175303-A1 | SYNTHESIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-06-23 | — | — | US | claimed |
| US-20120095021-A1 | SYNTHSIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2012-04-19 | — | — | US | claimed |
| CN-118702646-A | Novel polymerizable liquid crystal | 罗利克技术有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-114026078-B | Novel polymerizable liquid crystal | 罗利克技术有限公司 | 2024-06-07 | — | — | CN | disclosed |
| EP-3990569-A1 | NEW POLYMERIZABLE LIQUID CRYSTAL | Rolic Technologies AG (CH) | 2022-05-04 | — | — | EP | disclosed |
| CN-114026078-A | Novel polymerizable liquid crystal | 罗利克技术有限公司 | 2022-02-08 | — | — | CN | disclosed |
| WO-2020260624-A1 | NEW POLYMERIZABLE LIQUID CRYSTAL | Rolic Technologies AG (CH) | 2020-12-30 | — | — | WO | disclosed |
| US-10729671-B2 | Zinc complexes of hydrazones and (thio)semicarbazones and their use for the treatment of cancer | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2020-08-04 | — | — | US | disclosed |
| US-9949970-B2 | Synthesis of new benzothiazole derivatives as potential anti-tubercular agents | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-04-24 | — | — | US | disclosed |
| US-20180000772-A1 | ZINC COMPLEXES OF HYDRAZONES AND (THIO)SEMICARBAZONES AND THEIR USE FOR THE TREATMENT OF CANCER | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-01-04 | — | — | US | disclosed |
| US-20160175303-A1 | SYNTHESIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-06-23 | — | — | US | disclosed |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | HAGIYA KOJI | 2009-08-27 | — | — | US | disclosed |
| US-7554000-B2 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| WO-2008121861-A2 | PYRAZOLE AND PYRROLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-09 | — | — | WO | disclosed |
| WO-2008118790-A1 | DIHYDROINDAZOLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-10-02 | — | — | WO | disclosed |
| US-20080234327-A1 | DIHYDROINDAZOLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | XENON PHARMACEUTICALS INC. (CA) | 2008-09-25 | — | — | US | disclosed |
| CN-1303043-C | Process for producing biaryl compound | SUMITOMO CHEMICAL CO (JP) | 2007-03-07 | — | — | CN | disclosed |
| CN-1642879-A | Process for preparing diaryl compounds | SUMITOMO CHEMICAL CO (JP) | 2005-07-20 | — | — | CN | disclosed |
| US-20050096471-A1 | Process for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-05-05 | — | — | US | disclosed |
| EP-1473286-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2004-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10729671-B2 | Zinc complexes of hydrazones and (thio)semicarbazones and their use for the treatment of cancer | SLC39A3, SLC39A7, SLC30A7 | MAPT 3462/4885KMT2A 1403/4885MEN1 1414/4885 |
| US-20180000772-A1 | ZINC COMPLEXES OF HYDRAZONES AND (THIO)SEMICARBAZONES AND THEIR USE FOR THE TREATMENT OF CANCER | SLC39A3, SLC39A7, SLC30A7 | MAPT 3462/4885KMT2A 1403/4885MEN1 1414/4885 |
| US-20160175303-A1 | SYNTHESIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS | TST, TBCA, SDHA | MAPT 1450/4885KMT2A 3916/4885MEN1 3843/4885 |
| US-20120095021-A1 | SYNTHSIS OF NEW BENZOTHIAZOLE DERIVATIVES AS POTENTIAL ANTI-TUBERCULAR AGENTS | TST, SDHB, SDHA | MAPT 1492/4885KMT2A 4072/4885MEN1 3854/4885 |
| US-20090216017-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | PPOX, CAT, TYR | MAPT 3403/4885KMT2A 575/4885MEN1 3325/4885 |
| US-20080234327-A1 | DIHYDROINDAZOLE COMPOUNDS USEFUL IN TREATING IRON DISORDERS | FECH, SLC40A1, HAMP | MAPT 401/4885KMT2A 1932/4885MEN1 691/4885 |
| US-20050096471-A1 | Process for producing biaryl compound | PPOX, CAT, TYR | MAPT 3403/4885KMT2A 575/4885MEN1 3325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.