Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | GNRHR | P30968 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TK1 | P04183 | 1/20 | 0.34 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15206781 | 0.83 | ALDH1A1 (0.40) | KMT2AALDH1A1TSHRMAPK14MAOA | |
| SCHEMBL15206814 | 0.83 | ALDH1A1 (0.42) | KMT2AALDH1A1TSHRCYP2C19L3MBTL1 | |
| SCHEMBL6719842 | 0.75 | ALDH1A1 (0.52) | KMT2AALDH1A1TSHRCYP2C9CYP2C19 | |
| SCHEMBL21178006 | 0.74 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1TSHRCYP2C9 | |
| SCHEMBL21190333 | 0.73 | HPGD (0.39) | KMT2AMEN1ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL20012332 | 0.73 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1L3MBTL1MAOA | |
| SCHEMBL21179153 | 0.72 | LMNA (0.45) | KMT2AMEN1ALDH1A1TSHRCYP2C9 | |
| SCHEMBL7872863 | 0.72 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1TK1 | |
| SCHEMBL19147802 | 0.72 | MEN1 (0.52) | KMT2AMEN1ALDH1A1TSHRGNRHR | |
| SCHEMBL7640992 | 0.69 | MEN1 (0.47) | KMT2AMEN1ALDH1A1TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111801339-B | 5-Fluorouracil compounds | 纽科利制药公司 | 2025-06-24 | — | — | CN | disclosed |
| US-11427550-B2 | 5-fluorouracil compounds | NUCORION PHARMACEUTICALS, INC. (US) | 2022-08-30 | — | — | US | disclosed |
| US-20200399227-A1 | 5-FLUOROURACIL COMPOUNDS | NUCORION PHARMACEUTICALS, INC. | 2020-12-24 | — | — | US | disclosed |
| US-20200399227-A1 | 5-FLUOROURACIL COMPOUNDS | NUCORION PHARMACEUTICALS, INC. | 2020-12-24 | — | — | US | disclosed |
| CN-111801339-A | 5-fluorouracil compounds | 纽科利制药公司 | 2020-10-20 | — | — | CN | disclosed |
| WO-2019143860-A1 | 5-FLUOROURACIL COMPOUNDS | NUCORION PHARMACEUTICALS, INC. (US) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200399227-A1 | 5-FLUOROURACIL COMPOUNDS | DPYD, DHFR, FAU | KMT2A 2793/4885MEN1 447/4885ALDH1A1 240/4885 |
| US-11427550-B2 | 5-fluorouracil compounds | DPYD, DHFR, MTHFD1 | KMT2A 3192/4885MEN1 588/4885ALDH1A1 104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.