Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | HBB | P68871 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510420 | 0.96 | GMNN (0.41) | BBOX1GMNNALDH1A1LMNATP53 | |
| Potassium Ion SCHEMBL9347192 | 0.87 | BBOX1 (0.32) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL8501464 | 0.84 | GMNN (0.39) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL9510740 | 0.83 | KDM4E (0.37) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL563029 | 0.81 | APP (0.39) | LMNACES1EPHX2CES2 | |
| SCHEMBL2121030 | 0.79 | APP (0.38) | LMNACES1EPHX2CES2 | |
| SCHEMBL7594010 | 0.79 | CES1 (0.32) | CES1CES2 | |
| SCHEMBL9419170 | 0.79 | APP (0.38) | LMNACES1EPHX2CES2 | |
| Methacrylic Acid SCHEMBL28000398 | 0.79 | TSHR (0.38) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL9813622 | 0.78 | GMNN (0.44) | BBOX1GMNNALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3535325-A1 | LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS | Milliken & Company (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-3535371-A1 | LEUCO POLYMERS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS | The Procter & Gamble Company (US) | 2019-09-11 | — | — | EP | disclosed |
| EP-2445479-B1 | ORAL CARE COMPOSITIONS COMPRISING A POLYMERIC DYE | UNILEVER PLC (GB) | 2016-09-07 | — | — | EP | disclosed |
| US-9138600-B2 | Oral care compositions comprising a polymeric dye | CONOPCO, INC. (US) | 2015-09-22 | — | — | US | disclosed |
| EP-2547321-A2 | METHOD OF TREATING HAIR | Unilever PLC (GB) | 2013-01-23 | — | — | EP | disclosed |
| EP-2547319-A2 | METHOD OF TREATING HAIR | Unilever PLC (GB) | 2013-01-23 | — | — | EP | disclosed |
| US-20120093905-A1 | ORAL CARE COMPOSITIONS COMPRISING A POLYMERIC DYE | CONOPCO, INC., D/B/A UNILEVER | 2012-04-19 | — | — | US | disclosed |
| WO-2011113249-A1 | METHOD OF TREATING HAIR | UNILEVER PLC (GB) | 2011-09-22 | — | — | WO | disclosed |
| WO-2011113675-A2 | METHOD OF TREATING HAIR | UNILEVER PLC (GB) | 2011-09-22 | — | — | WO | disclosed |
| WO-2011113676-A2 | METHOD OF TREATING HAIR | UNILEVER PLC (GB) | 2011-09-22 | — | — | WO | disclosed |
| US-4994088-A | Amphoteric polymer, water soluble inorganic salt, oil or fat, cationic surfactant, water or aqueous alcohol | KAO CORPORATION (JP) | 1991-02-19 | — | — | US | disclosed |
| EP-0217274-A2 | Hair cosmetic composition | Kao Corporation (JP) | 1987-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120093905-A1 | ORAL CARE COMPOSITIONS COMPRISING A POLYMERIC DYE | FHIT, KRTCAP2, DSC1 | BBOX1 2496/4885GMNN 508/4885ALDH1A1 3164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.