Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | HBB | P68871 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9510740 | 0.95 | KDM4E (0.37) | BBOX1KDM4EMAPTALOX15TDP1 | |
| Potassium Ion SCHEMBL2121027 | 0.87 | BBOX1 (0.39) | BBOX1KDM4EMAPTALOX15GMNN | |
| SCHEMBL8503742 | 0.83 | KDM4E (0.34) | BBOX1KDM4EMAPTALOX15GMNN | |
| SCHEMBL9510420 | 0.83 | GMNN (0.41) | BBOX1KDM4EMAPTALOX15GMNN | |
| SCHEMBL536402 | 0.79 | PTGS1 (0.35) | TDP1LMNA | |
| SCHEMBL9513534 | 0.77 | PTGS1 (0.33) | TDP1LMNA | |
| Potassium SCHEMBL9347201 | 0.77 | PTGS1 (0.33) | TDP1LMNA | |
| SCHEMBL15759387 | 0.74 | TDP1 (0.44) | TDP1ALDH1A1LMNATSHRMAPK1 | |
| Methacrylic Acid SCHEMBL28401780 | 0.74 | BBOX1 (0.31) | BBOX1KDM4EMAPTALOX15ALDH1A1 | |
| SCHEMBL22264055 | 0.74 | BBOX1 (0.53) | BBOX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370646-B1 | Apparatus and method for the manufacture of absorbent materials | NIPPON CATALYTIC CHEM IND (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-5098775-A | Absorbent addition polymer on one surface, sanitary napkins, diapers | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1992-03-24 | — | — | US | disclosed |
| US-5079034-A | Good adhesion to substrate | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0370646-A2 | Apparatus and method for the manufacture of absorbent materials | NIPPON SHOKUBAI CO., LTD. (JP) | 1990-05-30 | — | — | EP | disclosed |