Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL212523 | 0.94 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL215012 | 0.93 | KIT (0.30) | KIT | |
| SCHEMBL213271 | 0.88 | SCD5 (0.34) | — | |
| SCHEMBL210927 | 0.88 | KDM4E (0.37) | — | |
| SCHEMBL211532 | 0.87 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL2725394 | 0.87 | P2RX7 (0.31) | KIT | |
| SCHEMBL212588 | 0.86 | MAPT (0.34) | — | |
| SCHEMBL212048 | 0.85 | POLB (0.35) | — | |
| SCHEMBL212349 | 0.84 | MAPT (0.34) | — | |
| SCHEMBL212791 | 0.83 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088793-B2 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |