Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831186 | 0.82 | ALDH1A1 (0.58) | KMT2AMEN1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL27529410 | 0.82 | ALDH1A1 (0.60) | KMT2AMEN1MAPTPSIP1SMN1; SMN2 | |
| SCHEMBL28079516 | 0.81 | CA1 (0.56) | SMN1; SMN2ALDH1A1CA1CA2MMP1 | |
| SCHEMBL27990218 | 0.80 | ALDH1A1 (0.55) | KMT2AMEN1MAPTPSIP1SMN1; SMN2 | |
| SCHEMBL11086966 | 0.79 | MAPK1 (0.58) | KMT2AMAPTSMN1; SMN2ALDH1A1CA1 | |
| SCHEMBL8761040 | 0.79 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1TSHRKDM4EMAPK1 | |
| SCHEMBL28326525 | 0.79 | L3MBTL1 (0.60) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL28313674 | 0.79 | KEAP1 (0.49) | KMT2AMAPTSMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL10837819 | 0.78 | KMT2A (0.64) | KMT2ASMN1; SMN2ALDH1A1CA1CA2 | |
| SCHEMBL10407475 | 0.77 | ALDH1A1 (0.49) | KMT2AMEN1SMN1; SMN2ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110642791-A | Sulfonylurea compound, preparation method thereof and application thereof in preparing herbicide | 南开大学 | 2020-01-03 | — | — | CN | claimed |
| CN-101111240-B | Isolation of n-butylbenzenesulfonamide, synthesis of benzenesulfonamide derivatives, and use of n-butylbenzenesulfonamide and benzenesulfonamide derivatives for the treatment of benign prostate hyperp | LOHMANN THERAPIE SYST LTS | 2011-09-21 | — | — | CN | claimed |
| CN-114585605-B | Pharmaceutical compounds | 圣提内尔肿瘤学有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-114846000-B | 2-Amino-N- (amino-oxo-aryl-lambda 6-sulfinyl) acetamide compounds and therapeutic uses thereof | 牛津药物设计有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-20240400536-A1 | IDEBENONE DERIVATIVES AND THEIR USE IN TREATING PLANTS | MITORX THERAPEUTICS LTD (GB) | 2024-12-05 | — | — | US | disclosed |
| CN-110396085-B | Combination therapy | 爱尔康公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-113891891-B | Modulators of AMPA receptor signaling | 戒毒及精神健康中心 | 2024-10-11 | — | — | CN | disclosed |
| CN-113950476-B | Substituted 4- [5- (benzofuran-2-yl) -1,2, 4-oxadiazol-3-yl ] benzoic acid compounds for the treatment of neuropathic pain | 伦敦皇家学院 | 2024-08-16 | — | — | CN | disclosed |
| CN-118234716-A | Idebenone derivatives and their use in the treatment of plants | 米托克斯治疗有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-117813121-A | Biphosphine compounds and complexes | 癌症研究技术有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117642395-A | Azetidinyl pyrimidines and their use | 爱瑞制药公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2003068226-A1 | 2-OXAZOLAMINES AND THEIR USE AS 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |
| WO-2003068227-A1 | 5-HT2B RECEPTOR ANTAGONISTS | PHARMAGENE LABORATORIES LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |
| EP-1330442-A1 | PHTHALAZINONE DERIVATIVES | Kudos Pharmaceuticals Limited (GB) | 2003-07-30 | — | — | EP | disclosed |
| EP-1305026-A2 | BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS | Novuspharma S.p.A. (IT) | 2003-05-02 | — | — | EP | disclosed |
| WO-2003024949-A1 | DNA-PK INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |
| WO-2003015790-A1 | THIOPYRANE-4-ONES AS DNA PROTEIN KINASE INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2003-02-27 | — | — | WO | disclosed |
| WO-2002090334-A1 | ISOQUINOLINONE DERIVATIVES AS PARP INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002036576-A1 | PHTHALAZINONE DERIVATIVES | KUDOS PHARMACEUTICALS LIMITED (GB) | 2002-05-10 | — | — | WO | disclosed |
| WO-2001093841-A2 | BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS | NOVUSPHARMA S.P.A. (IT) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400536-A1 | IDEBENONE DERIVATIVES AND THEIR USE IN TREATING PLANTS | AIFM1, TUFM, SQOR | KMT2A 4827/4885MEN1 4628/4885MAPT 2216/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.