Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18814368 | 1.00 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL18811817 | 1.00 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL25619253 | 0.88 | SMN1; SMN2 (0.39) | ALDH1A1LMNASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL21261915 | 0.85 | SMYD3 (0.39) | ALDH1A1LMNASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL20626544 | 0.82 | ITGB1 (0.36) | ALDH1A1LMNASMN1; SMN2EPHX2 | |
| SCHEMBL9516460 | 0.79 | ALDH1A1 (0.69) | ALDH1A1LMNASMN1; SMN2EPHX2KMT2A | |
| SCHEMBL2754993 | 0.78 | LMNA (0.56) | ALDH1A1LMNASMN1; SMN2MMP2MMP9 | |
| SCHEMBL23323338 | 0.76 | EPHX2 (0.40) | SMN1; SMN2EPHX2 | |
| SCHEMBL24032975 | 0.76 | ITGB1 (0.33) | LMNASMN1; SMN2EPHX2 | |
| SCHEMBL23552243 | 0.76 | EPHX2 (0.40) | SMN1; SMN2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190247407-A1 | DENDRIMER BASED NANODEVICES FOR THERAPEUTIC AND IMAGING PURPOSES | Ashvattha Therapeutics, Inc. | 2019-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190247407-A1 | DENDRIMER BASED NANODEVICES FOR THERAPEUTIC AND IMAGING PURPOSES | PAM, MUC1, AADAC | ALDH1A1 2164/4885LMNA 2887/4885SMN1; SMN2 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.