Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 6/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.42 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.41 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17742350 | 0.76 | SIRT2 (0.69) | SIRT2SIRT1SIRT5ECE1MMP3 | |
| SCHEMBL24774255 | 0.76 | LTA4H (0.49) | LTA4HSIRT2SIRT1MMP3KLKB1 | |
| SCHEMBL6287961 | 0.74 | SIRT2 (0.60) | LTA4HSIRT2SIRT1SIRT5MMP3 | |
| SCHEMBL21726052 | 0.74 | CA1 (0.51) | LTA4HSIRT2SIRT1SIRT5MMP3 | |
| SCHEMBL23729020 | 0.73 | LTA4H (0.49) | LTA4HMMP3KLKB1CA1CA2 | |
| SCHEMBL16418621 | 0.73 | KLKB1 (0.49) | LTA4HSIRT2SIRT1MMP3KLKB1 | |
| SCHEMBL14872058 | 0.72 | SSTR3 (0.55) | LTA4HSIRT2SIRT1ECE1MMP3 | |
| SCHEMBL17706674 | 0.72 | SSTR3 (0.55) | LTA4HSIRT2SIRT1SIRT5ECE1 | |
| SCHEMBL14821040 | 0.72 | SSTR3 (0.55) | LTA4HSIRT2SIRT1SIRT5ECE1 | |
| SCHEMBL18494988 | 0.72 | SSTR3 (0.55) | LTA4HSIRT2SIRT1SIRT5ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154120-A1 | CYTOTOXIC AGENT AND CONJUGATE THEREOF, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-08-15 | — | — | WO | disclosed |