SCHEMBL2127159

SCHEMBL2127159

CC(C)(C)OC(=O)C1C(CO)C1(C)C

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.33
MAPK1 P28482 1/20 0.33
APLNR P35414 1/20 0.31
ALOX15 P16050 1/20 0.31
ABCB1 P08183 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27350400 0.83 MAPK1 (0.33) MAPK1APLNR
SCHEMBL295406 0.80 MAPK1 (0.31) MAPK1
SCHEMBL1149796 0.79 LMNA (0.32) MAPK1
SCHEMBL1149836 0.78 POLA1 (0.35) ALOX15
SCHEMBL1149832 0.78 POLA1 (0.35) ALOX15
SCHEMBL1150584 0.78 POLA1 (0.35) ALOX15
SCHEMBL1149830 0.78 POLA1 (0.35) ALOX15
SCHEMBL1150587 0.78 POLA1 (0.35) ALOX15
SCHEMBL2709838 0.78 PRKCA (0.30)
SCHEMBL1685676 0.76 NAAA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1535895-B1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS SUMITOMO CHEMICAL CO (JP) 2012-04-25 EP disclosed
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids SUMITOMO CHEMICAL COMPAY LIMTED (JP) 2005-12-29 US disclosed
US-20050240050-A1 Process for production of formylcyclopropanecarboxylic ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-10-27 US disclosed
EP-1538141-A1 PROCESS FOR PRODUCTION OF 2-(HYDROXYMETHYL)CYCLO- PROPANECARBOXYLIC ACIDS Sumitomo Chemical Company, Limited (JP) 2005-06-08 EP disclosed
EP-1535895-A1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS Sumitomo Chemical Company, Limited (JP) 2005-06-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288526-A1 Process for production of 2-(hydroxymethyl)cyclo-propanecarboxylic acids GRHPR, PCCA, C5 NR1H2 1938/4885MAPK1 1510/4885APLNR 3277/4885
US-20050240050-A1 Process for production of formylcyclopropanecarboxylic ester AHCYL1, HACL2, CBR1 NR1H2 1525/4885MAPK1 1994/4885APLNR 1844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.