SCHEMBL2127252

SCHEMBL2127252

[CH2]CC[SiH2]C(OCCCC)OCCCC

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.31
ADRB2 P07550 1/20 0.31
ADRB1 P08588 1/20 0.31
ADRB3 P13945 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4079098 0.87
SCHEMBL703595 0.87 ADRB2 (0.36) DNM1ADRB2ADRB1ADRB3
SCHEMBL706696 0.85 ADRB2 (0.35) DNM1ADRB2ADRB1ADRB3
SCHEMBL705365 0.85 ADRB2 (0.35) DNM1ADRB2ADRB1ADRB3
SCHEMBL4090919 0.83 DNM1 (0.33) DNM1ADRB2ADRB1ADRB3
SCHEMBL2552187 0.79 DNM1 (0.39) DNM1ADRB2ADRB1ADRB3
SCHEMBL703587 0.78 ADRB2 (0.36) DNM1ADRB2ADRB1ADRB3
SCHEMBL1066786 0.78 THRB (0.35)
SCHEMBL375870 0.78 DNM1 (0.31) DNM1ADRB2ADRB1ADRB3
SCHEMBL7760600 0.78 TSHR (0.39) DNM1ADRB2ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1915399-B1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES COATINGS FOREIGN IP CO LLC (US) 2013-11-20 EP claimed
US-8030422-B2 Recoverable polymer-bound homogeneous catalysts for catalytic chain transfer process E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-10-04 US claimed
EP-1915399-A1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES E.I.Du pont de nemours and company (US) 2008-04-30 EP claimed
WO-2007024634-A1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-03-01 WO claimed
EP-0791016-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-27 EP claimed
WO-1996015157-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-23 WO claimed
EP-2970538-B1 POLYMERIZATION PROCESS PROTECTION MEANS DUPONT ELECTRONICS INC (US) 2021-10-20 EP disclosed
CN-107428955-B Proton binding polymers for oral administration 特里赛达公司 2021-09-21 CN disclosed
US-9925214-B2 Proton-binding polymers for oral administration TRICIDA, INC. (US) 2018-03-27 US disclosed
WO-2016123675-A1 TARGETING CONSTRUCTS FOR DELIVERY OF PAYLOADS THE UNIVERSITY OF QUEENSLAND (AU) 2016-08-11 WO disclosed
US-20160074430-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION RENIBUS THERAPEUTICS, INC. 2016-03-17 US disclosed
EP-2970538-A1 POLYMERIZATION PROCESS PROTECTION MEANS E. I. du Pont de Nemours and Company (US) 2016-01-20 EP disclosed
WO-2014150700-A1 POLYMERIZATION PROCESS PROTECTION MEANS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-09-25 WO disclosed
WO-2007070724-A2 PIGMENT DISPERSIONS CONTAINING AMINATED ACRYLIC MACROMONOMER DISPERSANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-06-21 WO disclosed
EP-1786552-A1 METHOD OF MAKING POLYMER MONOLITH COMPOSITE SUBSTRATE AND RESULTING SUBSTRATE AS WELL AS BEADS AND BEAD ARRAY Applera Corporation (US) 2007-05-23 EP disclosed
WO-2007024634-A1 RECOVERABLE POLYMER-BOUND HOMOGENEOUS CATALYSTS FOR CATALYTIC CHAIN TRANSFER PROCESSES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-03-01 WO disclosed
US-20060078983-A1 Polymer monolith substrate APPLERA CORPORATION (US) 2006-04-13 US disclosed
EP-1639019-A1 PRESSURIZED HIGH TEMPERATURE POLYMERIZATION PROCESS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-03-29 EP disclosed
WO-2006026378-A1 METHOD OF MAKING POLYMER MONOLITH COMPOSITE SUBSTRATE AND RESULTING SUBSTRATE AS WELL AS BEADS AND BEAD ARRAY APPLERA CORPORATION (US) 2006-03-09 WO disclosed
WO-2005003185-A1 PRESSURIZED HIGH TEMPERATURE POLYMERIZATION PROCESS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2005-01-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160074430-A1 PROTON-BINDING POLYMERS FOR ORAL ADMINISTRATION SLC9A1, HRH2, SLC9A2 DNM1 650/4885ADRB2 4338/4885ADRB1 4371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.