Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Propionic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.46 |
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.44 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.41 |
| ▸ | FFAR3 | O14843 | 4/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL11170639 | 1.00 | FFAR3 (0.67) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL11213687 | 1.00 | FFAR3 (0.67) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL18911561 | 1.00 | FFAR3 (0.67) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL18838064 | 0.97 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL28007958 | 0.97 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL5732953 | 0.97 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL27855764 | 0.97 | FFAR3 (0.62) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL11251003 | 0.93 | FFAR3 (0.67) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL8596099 | 0.93 | FFAR3 (0.67) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Propionic Acid SCHEMBL9350568 | 0.93 | FFAR3 (0.67) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240287409-A1 | CHELATE-AMPHOTERIC SURFACTANT LIQUID CONCENTRATES AND USE THEREOF IN CLEANING APPLICATIONS | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2024-08-29 | — | — | US | claimed |
| EP-4363541-A1 | CHELATE-AMPHOTERIC SURFACTANT LIQUID CONCENTRATES AND USE THEREOF IN CLEANING APPLICATIONS | Nouryon Chemicals International B.V. (NL) | 2024-05-08 | — | — | EP | claimed |
| CN-117679362-A | Veterinary valnemulin solution and preparation method and application thereof | 广东温氏大华农生物科技有限公司 | 2024-03-12 | — | — | CN | claimed |
| CN-116098991-A | Pharmaceutical compositions containing glucagon conjugates and uses thereof | 派格生物医药(苏州)股份有限公司 | 2023-05-12 | — | — | CN | claimed |
| WO-2023275269-A1 | CHELATE-AMPHOTERIC SURFACTANT LIQUID CONCENTRATES AND USE THEREOF IN CLEANING APPLICATIONS | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2023-01-05 | — | — | WO | claimed |
| CN-108440355-B | Thioether compound and synthesis method and application thereof | 浙江大学宁波理工学院 | 2020-11-27 | — | — | CN | claimed |
| CN-107167356-B | Coloring agent capable of quickly developing color after cells in urine are colored and using method thereof | 迪瑞医疗科技股份有限公司 | 2020-02-04 | — | — | CN | claimed |
| CN-109912472-A | Method for continuously and rapidly synthesizing 2-hydroxy-4-methylthiobutyronitrile | 禄丰天宝磷化工有限公司 | 2019-06-21 | — | — | CN | claimed |
| CN-108440355-A | A kind of thio-ether type compounds and its synthetic method and purposes | 浙江大学宁波理工学院 | 2018-08-24 | — | — | CN | claimed |
| CN-107167356-A | In a kind of urine after cell dyeing quick colour-developing coloring agent and its application method | 迪瑞医疗科技股份有限公司 | 2017-09-15 | — | — | CN | claimed |
| CN-103071146-A | Caspofungin acetate composition and preparation method thereof | BEIJING JESKONT PHARMACEUTICAL INTERNAT CO LTD | 2013-05-01 | — | — | CN | claimed |
| EP-3558903-B1 | PROCESS FOR PHOSPHORYLATING A COMPLEX ALCOHOL | AVECHO BIOTECHNOLOGY LTD (AU) | 2024-07-03 | — | — | EP | disclosed |
| CN-117679362-B | Veterinary valnemulin solution and preparation method and application thereof | 广东温氏大华农生物科技有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-117679362-A | Veterinary valnemulin solution and preparation method and application thereof | 广东温氏大华农生物科技有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-111683924-B | Highly stable and alkaline cleaning solutions and soluble surfactants | 赢创运营有限公司 | 2023-12-29 | — | — | CN | disclosed |
| CN-103071146-A | Caspofungin acetate composition and preparation method thereof | BEIJING JESKONT PHARMACEUTICAL INTERNAT CO LTD | 2013-05-01 | — | — | CN | disclosed |
| CN-102480944-A | Compositions containing sorbitan monocaprylate and antimicrobial actives | CLARIANT INT LTD | 2012-05-30 | — | — | CN | disclosed |
| CN-102438451-A | Composition containing sorbitan monocaprylate and alcohol | CLARIANT FINANCE BVI LTD | 2012-05-02 | — | — | CN | disclosed |
| US-20120101135-A1 | COMPOSITION CONTAINING SORBITAN MONOCAPRYLATE AND ANTIMICROBIAL SUBSTANCES | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-26 | — | — | US | disclosed |
| US-20120100085-A1 | COMPOSITION CONTAINING SORBITAN MONOCAPRYLATE AND ALCOHOL | CLARIANT FINANCE (BVI) LIMITED (VG) | 2012-04-26 | — | — | US | disclosed |