Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | WNT3A | P56704 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31257137 | 0.84 | TRPA1 (0.32) | ESR1ESR2CTNNB1WNT3ANPC1 | |
| SCHEMBL3976340 | 0.84 | TRPA1 (0.32) | ESR1ESR2CTNNB1WNT3ANPC1 | |
| SCHEMBL11049910 | 0.84 | ESR1 (0.38) | ESR1ESR2CTNNB1WNT3ANPC1 | |
| SCHEMBL31257139 | 0.84 | ESR1 (0.38) | ESR1ESR2CTNNB1WNT3ANPC1 | |
| SCHEMBL25990577 | 0.78 | P2RX7 (0.33) | ESR1ESR2CTNNB1WNT3ANPC1 | |
| SCHEMBL10550138 | 0.77 | NPC1 (0.33) | ESR1ESR2CTNNB1WNT3ANPC1 | |
| SCHEMBL10550141 | 0.77 | NPC1 (0.33) | ESR1ESR2CTNNB1WNT3ANPC1 | |
| SCHEMBL11049928 | 0.74 | ALDH1A1 (0.43) | CTNNB1WNT3ANPC1RAB9ALMNA | |
| SCHEMBL10736381 | 0.72 | CTNNB1 (0.36) | ESR1ESR2CTNNB1WNT3ANPC1 | |
| SCHEMBL10547082 | 0.72 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190262314-A1 | READY-TO-USE DEXMEDETOMIDINE COMPOSITIONS | SLAYBACK PHARMA LLC | 2019-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190262314-A1 | READY-TO-USE DEXMEDETOMIDINE COMPOSITIONS | OPRD1, OPRM1, DRD2 | ESR1 3987/4885ESR2 4697/4885CTNNB1 3592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.