SCHEMBL2129455

SCHEMBL2129455

OB(O)c1ccc(CS)cc1

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LPL P06858 7/20 0.58
LIPG Q9Y5X9 7/20 0.58
F11 P03951 1/20 0.56
CA2 P00918 3/20 0.50
CA1 P00915 2/20 0.50
ENPP2 Q13822 3/20 0.48
TRPV1 Q8NER1 1/20 0.47
MGLL Q99685 1/20 0.47
IDO1 P14902 4/20 0.46
TSHR P16473 1/20 0.46
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CA14 Q9ULX7 1/20 0.43
CA5B Q9Y2D0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7651263 0.80 LPL (0.61) LPLLIPGF11CA2CA1
SCHEMBL13667094 0.78 LPL (0.64) LPLLIPGF11CA2CA1
SCHEMBL890400 0.78 LPL (0.73) LPLLIPGF11CA2CA1
SCHEMBL204921 0.76 ENPP2 (0.73) LPLLIPGF11CA2CA1
SCHEMBL127369 0.76 IDO1 (0.69) IDO1TSHR
SCHEMBL112402 0.76 LPL (0.61) LPLLIPGF11CA2CA1
SCHEMBL23406327 0.74 LPL (0.58) LPLLIPGF11CA2CA1
SCHEMBL314531 0.74 LPL (0.58) LPLLIPGF11CA2CA1
SCHEMBL150306 0.74 LPL (1.00) LPLLIPGF11CA2CA1
SCHEMBL103171 0.74 F11 (0.95) LPLLIPGF11CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4674639-A1 TIRE Sumitomo Rubber Industries, Ltd. (JP) 2026-01-07 EP disclosed
CN-117362290-A Compound with anti-tumor activity, preparation method and application thereof 江苏海洋大学 2024-01-09 CN disclosed
CN-117203556-A High refractive index and high birefringence solid organic material 元平台技术有限公司 2023-12-08 CN disclosed
CN-111040204-B Force-induced response dynamic polymer and application thereof 厦门天策材料科技有限公司 2023-01-24 CN disclosed
CN-111378165-A Combined hybrid cross-linked dynamic polymer and application thereof 翁秋梅 2020-07-07 CN disclosed
CN-111378168-A Combined energy absorption method and application thereof 翁秋梅 2020-07-07 CN disclosed
CN-108752249-B Space conjugated organic molecule based on hexaarylbenzene skeleton and preparation and application thereof 华南理工大学 2020-06-19 CN disclosed
CN-111171365-A Force-responsive polymer foam composite material 翁秋梅 2020-05-19 CN disclosed
CN-111040204-A Force-induced response dynamic polymer and application thereof 翁秋梅 2020-04-21 CN disclosed
CN-111040203-A Energy absorption method based on hybrid cross-linked dynamic polymer 翁秋梅 2020-04-21 CN disclosed
US-20120245163-A1 TRPV1 Antagonists ABBOTT LABORATORIES (US) 2012-09-27 US disclosed
US-20120101103-A1 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES ARRAY BIOPHARMA INC. (US) 2012-04-26 US disclosed
EP-2379535-A1 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES Array Biopharma Inc. (US) 2011-10-26 EP disclosed
WO-2010075200-A1 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES ARRAY BIOPHARMA INC. (US) 2010-07-01 WO disclosed
US-20090042888-A1 Prostaglandin endoperoxide H synthase biosynthesis inhibitors BLACK LAWRENCE A 2009-02-12 US disclosed
EP-0783486-B1 NOVEL PROSTAGLANDIN SYNTHASE INHIBITORS DU PONT PHARM CO (US) 1999-10-13 EP disclosed
US-5932586-A ANTIINFLAMMATORY AGENTS; ANTIPYRETICS DUPONT PHARMACEUTICALS COMPANY (US) 1999-08-03 US disclosed
EP-0783486-A1 NOVEL PROSTAGLANDIN SYNTHASE INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1997-07-16 EP disclosed
US-5593994-A ANTIINFLAMMATORY AGENTS THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-01-14 US disclosed
WO-1996010012-A1 NOVEL PROSTAGLANDIN SYNTHASE INHIBITORS THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1996-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090042888-A1 Prostaglandin endoperoxide H synthase biosynthesis inhibitors PTGIS, PTGS1, PTGS2 LPL 1936/4885LIPG 854/4885F11 2230/4885
US-20120245163-A1 TRPV1 Antagonists TRPV1, TRPV3, TRPV6 LPL 1573/4885LIPG 2316/4885F11 2074/4885
US-20120101103-A1 7-PHENOXYCHROMAN CARBOXYLIC ACID DERIVATIVES PTGDR2, PTGDR, HRH2 LPL 4738/4885LIPG 4376/4885F11 1324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.