SCHEMBL2130164

SCHEMBL2130164

CC(=O)C/C=C(/CC(C)=O)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.34
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
LMNA P02545 1/20 0.30
ALOX15 P16050 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2130171 1.00 HTT (0.34) HTTMGAMGAASIMGAM2
SCHEMBL5512174 0.79 CPB1 (0.37) HTTMGAMGAASIMGAM2
SCHEMBL673568 0.77 HTT (0.34) HTTMGAMGAASIMGAM2
Acrylamide SCHEMBL28277012 0.77 ALDH1A1 (0.39)
SCHEMBL24358337 0.73 TRPA1 (0.36) TDP1LMNAALOX15BLMPMP22
SCHEMBL20379537 0.73 TRPA1 (0.36) TDP1LMNAALOX15BLMPMP22
SCHEMBL10817871 0.72
SCHEMBL10817873 0.72
Acetone SCHEMBL293563 0.71 TRPA1 (0.35) TDP1LMNAALOX15BLMPMP22
SCHEMBL9577379 0.70 MGAM (0.38) HTTMGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2629780-A2 IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS 206 ORTHO, Inc. (US) 2013-08-28 EP claimed
US-20120101593-A1 IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS BIOS2 Medical, Inc. (US) 2012-04-26 US claimed
WO-2012054742-A2 IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS BIOS2 Medical, Inc. (US) 2012-04-26 WO claimed
EP-0932652-B2 USE OF POLYMER DISPERSIONS AS BINDING AGENTS FOR SEALING COMPOUNDS AND COATING COMPOUNDS BASF SE (DE) 2008-04-23 EP claimed
EP-0932652-B1 USE OF POLYMER DISPERSIONS AS BINDING AGENTS FOR SEALING COMPOUNDS AND COATING COMPOUNDS BASF AG (DE) 2002-12-18 EP claimed
US-6242515-B1 ESPECIALLY SEALING POLYURETHANE FOAMS WITH A CURABLE MIXTURE OF AN ADDITION COPOLYMER CONTAINING CARBONYL GROUPS AND A DI-OR POLYCARBOXYLIC ACID HYDRAZIDE BASF AKTIENGESELLSCHAFT (DE) 2001-06-05 US claimed
EP-0932652-A1 USE OF POLYMER DISPERSIONS AS BINDING AGENTS FOR SEALING COMPOUNDS AND COATING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1999-08-04 EP claimed
US-5763012-A PROTECTIVE COATINGS AND SEALS BASF AKTIENGESELLSCHAFT (DE) 1998-06-09 US claimed
WO-1998016589-A1 USE OF POLYMER DISPERSIONS AS BINDING AGENTS FOR SEALING COMPOUNDS AND COATING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1998-04-23 WO claimed
EP-3838934-B1 ADHESIVE COMPOSITION FOR PAPER BONDING TESA SE (DE) 2025-05-14 EP disclosed
US-12054655-B2 Pressure-sensitive adhesive for paper bonds TESA SE (DE) 2024-08-06 US disclosed
US-20240123115-A1 IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS 206 ORTHO, INC. (US) 2024-04-18 US disclosed
US-11850323-B2 Implantable polymer for bone and vascular lesions 206 ORTHO, INC. (US) 2023-12-26 US disclosed
US-20210189191-A1 PRESSURE-SENSITIVE ADHESIVE FOR PAPER BONDS TESA SE (DE) 2021-06-24 US disclosed
EP-0046941-B1 THERMOPLASTIC MASS WITH INCREASED COHESIVE STRENGTH AND A MINOR FLOW-TENDENCY, AND PROCESS FOR ITSPREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1984-12-27 EP disclosed
US-4233163-A CURABLE POLYPHOSPHONATES STAUFFER CHEMICAL COMPANY (US) 1980-11-11 US disclosed
US-4076650-A COPPER SULFATE, HYDROGEN PEROXIDE CURING CATALYST FOR COPOLYCONDENSED OLIGOMERIC VINYL PHOSPHONATE STAUFFER CHEMICAL COMPANY (US) 1978-02-28 US disclosed
US-4067927-A TEXTILES STAUFFER CHEMICAL COMPANY (US) 1978-01-10 US disclosed
US-4052158-A CATALYTIC FREE RADICAL POLYMERIZATION, CURING STAUFFER CHEMICAL COMPANY (US) 1977-10-04 US disclosed
US-4017257-A Textiles fire-retardant treated with copolycondensed vinylphosphonates and process STAUFFER CHEMICAL COMPANY (US) 1977-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240123115-A1 IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS HPD, SMCHD1, IMPDH1 HTT 1792/4885MGAM 397/4885GAA 4065/4885
US-11850323-B2 Implantable polymer for bone and vascular lesions HPD, SMCHD1, IMPDH1 HTT 1792/4885MGAM 397/4885GAA 4065/4885
US-20120101593-A1 IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS BMP2, SOST, CD47 HTT 4270/4885MGAM 108/4885GAA 1121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.