Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116437 | 0.90 | PTGS2 (0.66) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL17365269 | 0.84 | PTGS2 (0.60) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL12061812 | 0.84 | GAA (0.66) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL7693991 | 0.82 | PTGS2 (0.58) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL13935133 | 0.82 | PTGS2 (0.58) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL5111012 | 0.82 | LMNA (0.69) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL197602 | 0.82 | PTGS2 (0.58) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL10364396 | 0.82 | PTGS2 (0.58) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL4264046 | 0.82 | PTGS2 (0.58) | PTGS2ALDH1A1CYP2C9CYP2C19MAPT | |
| SCHEMBL24844742 | 0.82 | GAA (0.73) | MAPTKMT2AL3MBTL1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230097293-A1 | LMP1 TARGETING LANTHANIDE COMPLEXES AND METHODS OF USE THEREOF | BP INNOMED LIMITED (CN) | 2023-03-30 | — | — | US | disclosed |
| WO-2021026479-A1 | SMALL MOLECULE INHIBITORS OF S1P2 RECEPTOR AND USES THEREOF | STAMFORD, ANDREW (US) | 2021-02-11 | — | — | WO | disclosed |
| US-10597409-B2 | Water-soluble triazapyridinophane-based complexing agents and corresponding fluorescent lanthanide complexes | CISBIO BIOASSAYS (FR) | 2020-03-24 | — | — | US | disclosed |
| WO-2017098180-A1 | WATER-SOLUBLE TRIAZAPYRIDINOPHANE-BASED COMPLEXING AGENTS AND CORRESPONDING FLUORESCENT LANTHANIDE COMPLEXES | CISBIO BIOASSAYS (FR) | 2017-06-15 | — | — | WO | disclosed |
| CN-105191992-A | Vegetable insecticide growth regulating agent | GONG CANFENG | 2015-12-30 | — | — | CN | disclosed |
| US-20120101039-A1 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2012-04-26 | — | — | US | disclosed |
| US-20120101039-A1 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2012-04-26 | — | — | US | disclosed |
| US-20120101039-A1 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2012-04-26 | — | — | US | disclosed |
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | disclosed |
| WO-2010136036-A2 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | LEO PHARMA A/S (DK) | 2010-12-02 | — | — | WO | disclosed |
| EP-1630165-B1 | [1,2,4]TRIAZOLO[1,5-a]PYRIMIDIN-2-YLUREA DERIVATIVE AND USE THEREOF | NIPPON KAYAKU KK (JP) | 2010-03-31 | — | — | EP | disclosed |
| CN-1174677-C | Plant growth regulator | 肖振英 | 2004-11-10 | — | — | CN | disclosed |
| WO-2000009116-A1 | GRP RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |
| WO-2000009115-A1 | GRP RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |
| US-5861421-A | 4,4-(disubstituted) cyclohexan-1-one monomers and related compounds | SMITHKLINE BEECHAM CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| EP-0800393-A4 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-ONE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0800393-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-ONE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996019995-A1 | 4,4-(DISUBSTITUTED)CYCLOHEXAN-1-ONE MONOMERS AND RELATED COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120101039-A1 | CALCIUM-SENSING RECEPTOR-ACTIVE COMPOUNDS | CASR, CALCR, PTH1R | PTGS2 958/4885ALDH1A1 4154/4885CYP2C9 4567/4885 |
| US-10597409-B2 | Water-soluble triazapyridinophane-based complexing agents and corresponding fluorescent lanthanide complexes | GSTA1, CLIC1, SLC40A1 | PTGS2 1208/4885ALDH1A1 390/4885CYP2C9 3445/4885 |
| US-20230097293-A1 | LMP1 TARGETING LANTHANIDE COMPLEXES AND METHODS OF USE THEREOF | EBNA1BP2, LAMP1, PML | PTGS2 4723/4885ALDH1A1 4703/4885CYP2C9 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.