SCHEMBL21332154

SCHEMBL21332154

CC(C)[Si](OC[C@]1(COCc2ccccc2)O[C@@H](n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1OCc1ccccc1)(C(C)C)C(C)C

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ P2RY6 Q15077 6/20 0.37
▸ P2RY2 P41231 6/20 0.37
▸ P2RY4 P51582 2/20 0.37
▸ P2RY12 Q9H244 6/20 0.36
▸ SLC28A1 O00337 1/20 0.36
▸ SLC28A2 O43868 1/20 0.36
▸ SLC29A1 Q99808 1/20 0.36
▸ SLC28A3 Q9HAS3 1/20 0.36
▸ NT5E P21589 1/20 0.36
▸ P2RY14 Q15391 1/20 0.34
▸ ST6GAL1 P15907 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23243983 0.87 TK1 (0.41) —
SCHEMBL20393996 0.86 NT5E (0.38) P2RY6P2RY2P2RY4P2RY12SLC28A1
SCHEMBL20393999 0.86 NT5E (0.38) P2RY6P2RY2P2RY4P2RY12SLC28A1
SCHEMBL1097719 0.86 SLC28A1 (0.43) P2RY6P2RY2P2RY4P2RY12SLC28A1
SCHEMBL18049482 0.85 P2RY6 (0.40) P2RY6P2RY2P2RY4P2RY12SLC28A1
SCHEMBL18049469 0.85 P2RY6 (0.40) P2RY6P2RY2P2RY4P2RY12SLC28A1
SCHEMBL25404146 0.85 P2RY6 (0.40) P2RY6P2RY2P2RY4P2RY12SLC28A1
SCHEMBL25400398 0.83 NT5E (0.39) P2RY6P2RY2P2RY4P2RY12SLC28A1
SCHEMBL13835027 0.81 NT5E (0.40) P2RY6P2RY2P2RY4P2RY12SLC28A1
SCHEMBL24066395 0.81 P2RY6 (0.39) P2RY6P2RY2P2RY4P2RY12SLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2026-04-16 — — US disclosed
CN-112105625-B Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same 赛诺菲 2024-12-31 — — CN disclosed
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI SA (FR) 2024-11-14 — — US disclosed
US-11897911-B2 Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same SANOFI (FR) 2024-02-13 — — US disclosed
US-20220372063-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2022-11-24 — — US disclosed
EP-4025582-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2022-07-13 — — EP disclosed
CN-114728999-A Oligonucleotides containing nucleotide analogs 赛诺菲 2022-07-08 — — CN disclosed
US-20210115075-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI (FR) 2021-04-22 — — US disclosed
WO-2021044004-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS SANOFI (FR) 2021-03-11 — — WO disclosed
EP-3762395-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME Sanofi (FR) 2021-01-13 — — EP disclosed
CN-112105625-A Nucleotide precursors, nucleotide analogs, and oligomeric compounds containing the same 赛诺菲 2020-12-18 — — CN disclosed
WO-2019170731-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME SANOFI (FR) 2019-09-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11897911-B2 Nucleotide precursors, nucleotide analogs and oligomeric compounds containing the same RNMT, RRM2B, RRM2 P2RY6 1244/4885P2RY2 1444/4885P2RY4 1792/4885
US-20210115075-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME RNMT, RRM2B, RRM2 P2RY6 1244/4885P2RY2 1444/4885P2RY4 1792/4885
US-20260103480-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME NSUN2, NSUN3, SNRPA P2RY6 2103/4885P2RY2 1252/4885P2RY4 2512/4885
US-20240376137-A1 NUCLEOTIDE PRECURSORS, NUCLEOTIDE ANALOGS AND OLIGOMERIC COMPOUNDS CONTAINING THE SAME RNMT, NSUN2, ADAR P2RY6 1665/4885P2RY2 1382/4885P2RY4 1745/4885
US-20220372063-A1 OLIGONUCLEOTIDES CONTAINING NUCLEOTIDE ANALOGS DCLRE1B, UPF1, IGF2BP1 P2RY6 4042/4885P2RY2 3960/4885P2RY4 4368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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