SCHEMBL21339613

SCHEMBL21339613

CCCCOC(=O)CCC(NC(=O)C1CCCN1C(C)=O)C(=O)NCCCCC(NC(=O)C(CCC(=O)OC(C)(C)C)NC(=O)C1CCCN1C(C)=O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ MMP1 P03956 1/20 0.41
▸ MMP3 P08254 1/20 0.41
▸ KMT2A Q03164 3/20 0.40
▸ MEN1 O00255 2/20 0.40
▸ APLNR P35414 1/20 0.39
▸ ITGB1 P05556 1/20 0.38
▸ ITGA4 P13612 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ GLP1R P43220 8/20 0.37
▸ GRB2 P62993 1/20 0.37
▸ ITGB3 P05106 2/20 0.37
▸ ITGA2B P08514 2/20 0.37
▸ CMA1 P23946 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21166986 0.81 ITGB3 (0.41) KMT2AMEN1APLNRITGB1ITGA4
SCHEMBL21339799 0.81 GLP1R (0.44) KMT2AMEN1ALDH1A1HPGDGLP1R
SCHEMBL22479117 0.79 ACE (0.33) MMP1MMP3KMT2AMEN1ITGB1
SCHEMBL21349175 0.77 ITGB1 (0.46) MMP1MMP3APLNRITGB1ITGA4
SCHEMBL21350659 0.76 MMP1 (0.32) MMP1MMP3KMT2AMEN1ITGB3
SCHEMBL24140122 0.75 ITGB1 (0.44) MMP1MMP3APLNRITGB1ITGA4
SCHEMBL21166987 0.75 ITGB3 (0.41) KMT2AMEN1APLNRITGB1ITGA4
SCHEMBL30391539 0.75 CMA1 (0.43) MMP1MMP3KMT2AMEN1ITGB3
SCHEMBL21167022 0.75 APLNR (0.46) MMP1MMP3APLNRITGB1ITGA4
SCHEMBL21339759 0.75 MMP3 (0.54) MMP1MMP3KMT2AITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11633460-B2 Injectable solution at pH 7 comprising at least one basal insulin wherein the pI is comprised from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals ADOCIA (FR) 2023-04-25 — — US disclosed
US-20220409523-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG AND A CO-POLYAMINO ACID ADOCIA (FR) 2022-12-29 — — US disclosed
US-11173109-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid ADOCIA (FR) 2021-11-16 — — US disclosed
US-10987426-B2 Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid ADOCIA (FR) 2021-04-27 — — US disclosed
US-20190274954-A1 Copositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid ADOCIA (FR) 2019-09-12 — — US disclosed
US-20190275156-A1 COMPOSITIONS SOUS FORME D'UNE SOLUTION AQUEUSE INJECTABLE COMPRENANT DU GLUCAGON HUMAIN ET UN CO-POLYAMINOACIDE ADOCIA (FR) 2019-09-12 — — US disclosed
US-20190275115-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHEREIN THE PI IS COMPRISED FORM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS ADOCIA (FR) 2019-09-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11633460-B2 Injectable solution at pH 7 comprising at least one basal insulin wherein the pI is comprised from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals IAPP, HBB, IGF1R MMP1 301/4885MMP3 2113/4885KMT2A 3929/4885
US-20190275156-A1 COMPOSITIONS SOUS FORME D'UNE SOLUTION AQUEUSE INJECTABLE COMPRENANT DU GLUCAGON HUMAIN ET UN CO-POLYAMINOACIDE GCG, GLP1R, GHSR MMP1 2515/4885MMP3 1731/4885KMT2A 3731/4885
US-20190274954-A1 Copositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid IAPP, GLP1R, INSR MMP1 1809/4885MMP3 3476/4885KMT2A 4797/4885
US-20220409523-A1 COMPOSITIONS IN THE FORM OF AN INJECTABLE AQUEOUS SOLUTION COMPRISING AMYLIN, AN AMYLIN RECEPTOR AGONIST OR AN AMYLIN ANALOG AND A CO-POLYAMINO ACID IAPP, INSR, GLP1R MMP1 1888/4885MMP3 3639/4885KMT2A 4716/4885
US-10987426-B2 Compositions in the form of an injectable aqueous solution comprising human glucagon and a co-polyamino acid GCG, GLP1R, GCGR MMP1 1887/4885MMP3 2378/4885KMT2A 1912/4885
US-11173109-B2 Compositions in the form of an injectable aqueous solution comprising amylin, an amylin receptor agonist or an amylin analog and a co-polyamino acid IAPP, INSR, GLP1R MMP1 2036/4885MMP3 3610/4885KMT2A 4745/4885
US-20190275115-A1 INJECTABLE SOLUTION AT PH 7 COMPRISING AT LEAST ONE BASAL INSULIN WHEREIN THE PI IS COMPRISED FORM 5.8 TO 8.5 AND A CO-POLYAMINO ACID BEARING CARBOXYLATE CHARGES AND HYDROPHOBIC RADICALS IAPP, GCG, HBB MMP1 437/4885MMP3 2290/4885KMT2A 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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