SCHEMBL21339770

SCHEMBL21339770

Nc1ccc(C2=NOC(C(F)(F)F)N2)cc1

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 2/20 0.36
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TP53 P04637 1/20 0.32
CYP3A4 P08684 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19070293 0.80 MAP2K4 (0.38) NPC1RAB9AALDH1A1TP53
SCHEMBL21238244 0.78 RXRA (0.40) NPC1RAB9AALDH1A1TP53
SCHEMBL21238143 0.77 CA2 (0.38)
SCHEMBL21339842 0.76 ADRB2 (0.36) CYP3A4
SCHEMBL21339828 0.75 HTR6 (0.38) CYP3A4
SCHEMBL21339826 0.75
SCHEMBL8293222 0.74 ALDH1A1 (0.36) NPC1RAB9AALDH1A1TP53CYP3A4
SCHEMBL21886870 0.73 CHRNB2 (0.40)
SCHEMBL21238117 0.73 KMT2A (0.44)
SCHEMBL21462400 0.71 RAB9A (0.46) NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019171234-A1 HETEROCYCLIC COMPOUNDS AS FUNGICIDES PI INDUSTRIES LTD. (IN) 2019-09-12 WO disclosed