Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 5/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24317412 | 0.85 | KMT2A (0.37) | KCNH2TMEM97SIGMAR1HTR1AKMT2A | |
| SCHEMBL15449628 | 0.77 | KIF11 (0.42) | KCNH2TMEM97SIGMAR1KMT2AHRH3 | |
| SCHEMBL12367365 | 0.75 | ADRA2A (0.44) | KCNH2TMEM97SIGMAR1KMT2AHRH3 | |
| SCHEMBL13243094 | 0.75 | KCNH2 (0.58) | KCNH2TMEM97SIGMAR1KMT2AMEN1 | |
| SCHEMBL2741665 | 0.75 | KCNH2 (0.38) | KCNH2TMEM97SIGMAR1KMT2AHRH3 | |
| SCHEMBL1101990 | 0.72 | MEN1 (0.55) | KCNH2KMT2AHRH3MEN1 | |
| SCHEMBL20119408 | 0.72 | ACACB (0.40) | KCNH2TMEM97SIGMAR1HTR1AKMT2A | |
| SCHEMBL27010070 | 0.72 | ABHD6 (0.47) | KCNH2TMEM97SIGMAR1 | |
| SCHEMBL20173789 | 0.72 | KCNH2 (0.37) | KCNH2TMEM97SIGMAR1KMT2AHRH3 | |
| SCHEMBL23716163 | 0.70 | HRH3 (0.43) | KCNH2KMT2AHRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190282703-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE (ENPP) CONJUGATES AND USES THEREOF | ABBVIE INC. | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190282703-A1 | ECTONUCLEOTIDE PYROPHOSPHATASE-PHOSPHODIESTERASE (ENPP) CONJUGATES AND USES THEREOF | ENPP1, ENPP3, ENPEP | KCNH2 4784/4885TMEM97 4711/4885SIGMAR1 4696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.