Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD5 | P21918 | 1/20 | 0.43 |
| ▸ | TIPARP | Q7Z3E1 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16624022 | 0.85 | ABHD6 (0.50) | ABHD6GABRA1GABRG2GABRB3DRD2 | |
| SCHEMBL27010059 | 0.85 | DRD2 (0.54) | GABRA1GABRG2GABRB3DRD2DRD3 | |
| SCHEMBL8036747 | 0.82 | KCNH2 (0.37) | KCNH2TMEM97SIGMAR1GABRA1GABRG2 | |
| SCHEMBL23711841 | 0.78 | GABRA1 (0.40) | KCNH2TMEM97SIGMAR1GABRA1GABRG2 | |
| SCHEMBL24702156 | 0.77 | DRD2 (0.55) | ABHD6GABRA1GABRG2GABRB3DRD2 | |
| SCHEMBL22334637 | 0.77 | DRD2 (0.54) | ABHD6DRD2DRD3DRD1DRD5 | |
| SCHEMBL15449628 | 0.77 | KIF11 (0.42) | KCNH2TMEM97SIGMAR1ALDH1A1HPGD | |
| SCHEMBL8027741 | 0.76 | KMT2A (0.46) | KCNH2TMEM97SIGMAR1GABRA1GABRG2 | |
| SCHEMBL13243094 | 0.75 | KCNH2 (0.58) | KCNH2TMEM97SIGMAR1DRD2DRD3 | |
| SCHEMBL12367365 | 0.75 | ADRA2A (0.44) | KCNH2TMEM97SIGMAR1TRAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | C 4 Therapeutics, Inc. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018118-A1 | TRICYCLIC COMPOUNDS TO DEGRADE NEOSUBSTRATES FOR MEDICAL THERAPY | NFATC1, CTSS, MMP12 | ABHD6 3261/4885KCNH2 4811/4885TMEM97 3680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.