Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 6/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21363954 | 0.87 | CYP2A6 (0.39) | LMNAALDH1A1ALOX5APFEN1CYP1A2 | |
| SCHEMBL21363961 | 0.77 | GABRA1 (0.38) | LMNAALDH1A1ALOX5APCYP1A2CYP2A6 | |
| SCHEMBL21364025 | 0.75 | S1PR4 (0.36) | LMNAALDH1A1ALOX15ALOX5APFEN1 | |
| SCHEMBL21363955 | 0.75 | NOS3 (0.37) | LMNATSHRALDH1A1ALOX5APFEN1 | |
| SCHEMBL21364096 | 0.74 | ALOX5AP (0.41) | LMNATSHRALDH1A1ALOX15ALOX5AP | |
| SCHEMBL14877377 | 0.71 | LMNA (0.50) | LMNATSHRALDH1A1ALOX15KCNH2 | |
| SCHEMBL21476134 | 0.70 | CYP2A6 (0.50) | HTR7CYP2A6 | |
| SCHEMBL3365805 | 0.69 | MEN1 (0.44) | CYP2A6 | |
| SCHEMBL12345157 | 0.68 | MKNK1 (0.50) | ALDH1A1 | |
| SCHEMBL27264144 | 0.67 | CYP1A2 (0.44) | LMNATSHRALDH1A1ALOX15HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11145821-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | SAMSUNG DISPLAY CO., LTD. (KR) | 2021-10-12 | — | — | US | disclosed |
| US-20190288216-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11145821-B2 | Organic electroluminescence device and polycyclic compound for organic electroluminescence device | LEF1, SLC25A21, EMC2 | LMNA 639/4885TSHR 4188/4885ALDH1A1 515/4885 |
| US-20190288216-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE | LEF1, SLC25A21, EMC2 | LMNA 639/4885TSHR 4188/4885ALDH1A1 515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.