SCHEMBL21364025

SCHEMBL21364025

Cc1ccc(C)c(-c2cncc(-c3c4ccccc4c(-c4cncc(-c5c(C)cccc5C)c4)c4ccccc34)c2)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 3/20 0.36
BRD4 O60885 1/20 0.34
KMT2A Q03164 4/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2A6 P11509 2/20 0.33
ADORA2A P29274 1/20 0.33
ALOX5AP P20292 1/20 0.33
FEN1 P39748 1/20 0.33
CTSA P10619 1/20 0.33
CHRNA7 P36544 1/20 0.33
LMNA P02545 2/20 0.33
TP53 P04637 2/20 0.33
MEN1 O00255 2/20 0.33
HPGD P15428 2/20 0.33
ALOX15 P16050 2/20 0.33
NPC1 O15118 1/20 0.33
GLA P06280 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21363954 0.86 CYP2A6 (0.39) BRD4KMT2ACYP1A2CYP2A6ADORA2A
SCHEMBL21364096 0.83 ALOX5AP (0.41) CYP1A2CYP2A6ADORA2AALOX5APFEN1
SCHEMBL21363958 0.75 LMNA (0.39) CYP1A2CYP2A6ALOX5APFEN1CTSA
SCHEMBL21363961 0.75 GABRA1 (0.38) CYP1A2CYP2A6ALOX5APLMNAKDM4E
SCHEMBL21364095 0.74 BRD4 (0.42) S1PR4BRD4KMT2ACYP1A2ALOX5AP
SCHEMBL21363955 0.74 NOS3 (0.37) KMT2ACYP1A2CYP2A6ALOX5APFEN1
SCHEMBL21476134 0.72 CYP2A6 (0.50) CYP2A6CHRNA7RAB9A
SCHEMBL21364094 0.71 TGFBR1 (0.40) S1PR4BRD4KMT2ACYP1A2LMNA
SCHEMBL21364075 0.71 TGFBR1 (0.45) BRD4CYP1A2CYP2A6ALOX5APFEN1
SCHEMBL26948394 0.70 PARP10 (0.43) KMT2ACYP2A6MEN1HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190288216-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190288216-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND POLYCYCLIC COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE LEF1, SLC25A21, EMC2 S1PR4 4298/4885BRD4 3820/4885KMT2A 2133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.