Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | DGKA | P23743 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139337 | 0.96 | DGKA (0.67) | TSHRDGKAALDH1A1NAAADNM1 | |
| SCHEMBL5272183 | 0.94 | DGKA (0.70) | TSHRDGKAALDH1A1NAAADNM1 | |
| SCHEMBL20564125 | 0.94 | DGKA (0.70) | TSHRDGKAALDH1A1NAAADNM1 | |
| SCHEMBL5269856 | 0.94 | DGKA (0.70) | TSHRDGKAALDH1A1NAAADNM1 | |
| SCHEMBL2138196 | 0.94 | DGKA (0.57) | TSHRDGKAALDH1A1NAAADNM1 | |
| SCHEMBL51177 | 0.91 | DGKA (0.71) | TSHRDGKAALDH1A1NAAADNM1 | |
| SCHEMBL25953980 | 0.90 | DGKA (0.66) | TSHRDGKANAAADNM1HTR2C | |
| SCHEMBL27736720 | 0.90 | DGKA (0.70) | TSHRDGKANAAADNM1HTR2C | |
| SCHEMBL5271388 | 0.89 | TSHR (0.65) | TSHRDGKAALDH1A1NAAADNM1 | |
| SCHEMBL11877869 | 0.88 | DGKA (0.74) | TSHRDGKAALDH1A1NAAADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7862749-B2 | Flame retardant polyurethanes and additives therefor | ALBEMARLE CORPORATION (US) | 2011-01-04 | — | — | US | disclosed |
| WO-2010017470-A1 | C7-FLUORO SUBSTITUTED TETRACYCLINE COMPOUNDS | TETRAPHASE PHARMACEUTICALS, INC. (US) | 2010-02-11 | — | — | WO | disclosed |
| EP-2107079-A2 | Flame retardants with high halogen content and low viscosity | Albermarle Corporation (US) | 2009-10-07 | — | — | EP | disclosed |
| CN-100537646-C | Flame retardants with high halogen content and low viscosity | ALBEMARLE CORP (US) | 2009-09-09 | — | — | CN | disclosed |
| EP-1664179-B1 | FLAME RETARDANTS WITH HIGH HALOGEN CONTENT AND LOW VISCOSITY | ALBEMARLE CORP (US) | 2009-07-15 | — | — | EP | disclosed |
| US-7381354-B2 | Flame retardants with high halogen content and low viscosity | ALBEMARLE CORPORATION (US) | 2008-06-03 | — | — | US | disclosed |
| US-20070276055-A1 | Flame Retardant Polyurethanes and Additives Therefor | ALBEMARLE CORPORATION (US) | 2007-11-29 | — | — | US | disclosed |
| EP-1478232-B1 | DIESTER DICARBOXYLATE ANTIMICROBIAL COMPOSITIONS AND METHODS EMPLOYING THEM | ECOLAB INC (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1756224-B1 | FLAME RETARDANT POLYURETHANES AND ADDITIVES THEREFOR | ALBEMARLE CORP (US) | 2007-10-17 | — | — | EP | disclosed |
| US-20070225517-A1 | Flame Retardants With High Halogen Content and Low Viscosity | ALBEMARLE CORPORATION (US) | 2007-09-27 | — | — | US | disclosed |
| US-20050045857-A1 | Flame retardants with high halogen content and low viscosity | ALBEMARLE CORPORATION | 2005-03-03 | — | — | US | disclosed |
| US-20050045858-A1 | Flame retardants with high halogen content and low viscosity | ALBEMARLE CORPORATION | 2005-03-03 | — | — | US | disclosed |
| EP-1478232-A1 | DIESTER DICARBOXYLATE ANTIMICROBIAL COMPOSITIONS AND METHODS EMPLOYING THEM | ECOLAB INC. (US) | 2004-11-24 | — | — | EP | disclosed |
| US-6627593-B2 | A high concentration monoester peroxy dicarboxylic acid composition comprising: 6 wt-% monoester peroxy dicarboxylic acid; about 10 wt-% diester dicarboxylate; anionic surfactant, amine oxide surfactant, or a mixture thereof; hydrogen | ECOLAB INC. | 2003-09-30 | — | — | US | disclosed |
| WO-2003073849-A1 | DIESTER DICARBOXYLATE ANTIMICROBIAL COMPOSITIONS AND METHODS EMPLOYING THEM | ECOLAB INC. (US) | 2003-09-12 | — | — | WO | disclosed |
| US-20030087786-A1 | High concentration monoester peroxy dicarboxylic acid compositions, use solutions, and methods employing them | ECOLAB USA INC. | 2003-05-08 | — | — | US | disclosed |
| US-20030021853-A1 | In situ mono-or diester dicarboxylate compositions | ECOLAB USA INC. | 2003-01-30 | — | — | US | disclosed |
| WO-2003005817-A2 | HIGH CONCENTRATION MONOESTER PEROXY DICARBOXYLIC ACID COMPOSITIONS, USE SOLUTIONS, AND METHODS EMPLOYING THEM | ECOLAB INC. (US) | 2003-01-23 | — | — | WO | disclosed |
| WO-2003005818-A1 | IN SITUMONO-OR DIESTER DICARBOXYLATE COMPOSITIONS | ECOLAB INC. (US) | 2003-01-23 | — | — | WO | disclosed |
| US-20020168422-A1 | Two solvent antimicrobial compositions and methods employing them | ECOLAB USA INC. | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030021853-A1 | In situ mono-or diester dicarboxylate compositions | DDC, HCAR3, ACMSD | TSHR 4231/4885DGKA 109/4885ALDH1A1 590/4885 |
| US-20020168422-A1 | Two solvent antimicrobial compositions and methods employing them | TAS2R50, HDHD5, CEL | TSHR 4520/4885DGKA 1221/4885ALDH1A1 2741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.