Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21390758 | 0.90 | HTR3A (0.31) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL21390956 | 0.81 | RORC (0.33) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL21390955 | 0.80 | ALDH1A1 (0.32) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL21390781 | 0.79 | BRD4 (0.33) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL21391134 | 0.79 | RORC (0.33) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL21390770 | 0.79 | ALDH1A1 (0.31) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL21390952 | 0.79 | RORC (0.34) | ALDH1A1MAPTMAPK1SMN1; SMN2NPSR1 | |
| SCHEMBL21390754 | 0.79 | NOS1 (0.33) | PDE4BPDE7APDE2APDE5APDE1B | |
| SCHEMBL20624489 | 0.79 | EGFR (0.37) | AGTR2AGTR1PDE4BPDE7APDE2A | |
| SCHEMBL19277960 | 0.79 | EGFR (0.37) | AGTR2AGTR1PDE4BPDE7APDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019183148-A1 | KV7 CHANNEL ACTIVATORS COMPOSITIONS AND METHODS OF USE | KNOPP BIOSCIENCES LLC (US) | 2019-09-26 | — | — | WO | disclosed |