Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | APLNR | P35414 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392073 | 0.83 | APLNR (0.42) | USP2TSHRAPLNRALDH1A1SMN1; SMN2 | |
| SCHEMBL30725701 | 0.83 | APLNR (0.42) | USP2TSHRAPLNRALDH1A1SMN1; SMN2 | |
| SCHEMBL21392246 | 0.78 | APLNR (0.35) | APLNRALDH1A1SMN1; SMN2HTTMEN1 | |
| SCHEMBL21392320 | 0.74 | USP2 (0.35) | USP2TSHRALDH1A1SMN1; SMN2HTT | |
| SCHEMBL28478417 | 0.73 | CASP6 (0.42) | ALDH1A1HTTMEN1KMT2ARAB9A | |
| SCHEMBL30518337 | 0.71 | HPGD (0.33) | TSHRALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL21392137 | 0.71 | HPGD (0.33) | TSHRALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL21392150 | 0.70 | RAB9A (0.32) | USP2TSHRALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL21392075 | 0.69 | ALDH1A1 (0.35) | USP2TSHRAPLNRALDH1A1SMN1; SMN2 | |
| SCHEMBL21392069 | 0.69 | APLNR (0.36) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180244-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |