Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21392320 | 0.82 | USP2 (0.35) | ALDH1A1LMNAMAPTUSP2TSHR | |
| SCHEMBL21392150 | 0.79 | RAB9A (0.32) | ALDH1A1LMNAMAPTUSP2TSHR | |
| SCHEMBL21392148 | 0.77 | LMNA (0.33) | ALDH1A1LMNAMAPTUSP2TSHR | |
| SCHEMBL21392074 | 0.69 | USP2 (0.35) | ALDH1A1LMNAMAPTUSP2TSHR | |
| SCHEMBL22762439 | 0.69 | LMNA (0.33) | ALDH1A1LMNAMAPTUSP2TSHR | |
| SCHEMBL21392076 | 0.68 | MLYCD (0.33) | ALDH1A1LMNAMAPTKMT2AMEN1 | |
| SCHEMBL21384620 | 0.66 | PTPN1 (0.39) | ALDH1A1LMNAMAPTUSP2TSHR | |
| SCHEMBL30725707 | 0.66 | PTPN1 (0.39) | ALDH1A1LMNAMAPTUSP2TSHR | |
| SCHEMBL21392292 | 0.64 | ALDH1A1 (0.35) | ALDH1A1LMNAMAPTUSP2TSHR | |
| SCHEMBL29937350 | 0.60 | LMNA (0.55) | ALDH1A1LMNAMAPTUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019180244-A1 | AMINOPYRIMIDINE DERIVATIVES AS CTPS1 INHIBITORS | STEP PHARMA S.A.S. (FR) | 2019-09-26 | — | — | WO | disclosed |