Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | PARL | Q9H300 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997654 | 0.91 | NR4A2 (0.49) | SMN1; SMN2RAB9ACYP1A2LMNAL3MBTL1 | |
| SCHEMBL28775907 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9ACYP1A2FFAR1LMNA | |
| SCHEMBL10720603 | 0.83 | L3MBTL1 (0.50) | SMN1; SMN2RAB9ALMNAL3MBTL1MAPT | |
| SCHEMBL11064187 | 0.83 | NPC1 (0.49) | SMN1; SMN2RAB9ALMNAL3MBTL1HPGD | |
| SCHEMBL4738882 | 0.80 | LMNA (0.51) | SMN1; SMN2RAB9ALMNAHPGDPARL | |
| SCHEMBL21993327 | 0.80 | MMP3 (0.52) | FFAR1LMNAPARLHDAC1HDAC8 | |
| SCHEMBL4872950 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2RAB9AHPGDPARLMAPT | |
| SCHEMBL27463054 | 0.77 | MGLL (0.42) | SMN1; SMN2RAB9ACYP1A2HPGDPARL | |
| SCHEMBL43576 | 0.76 | PSMB8 (0.35) | SMN1; SMN2LMNAHPGDPARLKMT2A | |
| SCHEMBL17521947 | 0.76 | ALDH1A1 (0.39) | SMN1; SMN2RAB9AHDAC1HDAC8KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210052748-A1 | NOVEL COMPOUND, ANTIINFLAMMATORY DRUG COMPRISING THE COMPOUND AND CYCLOOXYGENASE-2 INHIBITOR COMPRISING THE COMPOUND | CHANG, YONG MIN (KR) | 2021-02-25 | — | — | US | disclosed |
| WO-2019182395-A1 | COMPOUND HAVING NOVEL STRUCTURE, ANTI-INFLAMMATORY AGENT COMPRISING SAME, AND CYCLOOXYGENASE-2 INHIBITOR COMPRISING SAME | 장용민 | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210052748-A1 | NOVEL COMPOUND, ANTIINFLAMMATORY DRUG COMPRISING THE COMPOUND AND CYCLOOXYGENASE-2 INHIBITOR COMPRISING THE COMPOUND | PTGS2, PTGS1, PTGES2 | SMN1; SMN2 2447/4885RAB9A 4029/4885CYP1A2 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.