Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 7/20 | 0.47 |
| ▸ | WNT3A | P56704 | 7/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | MERTK | Q12866 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2035570 | 0.90 | PRKCI (0.49) | PRKCIDYRK1APOLBALDH1A1RAB9A | |
| SCHEMBL29791018 | 0.90 | PRKCI (0.49) | PRKCIDYRK1APOLBALDH1A1RAB9A | |
| SCHEMBL10366473 | 0.86 | CTNNB1 (0.49) | CTNNB1WNT3APRKCICLK1DYRK1A | |
| SCHEMBL29828764 | 0.83 | TAAR1 (0.53) | CTNNB1WNT3APRKCICLK1DYRK1A | |
| SCHEMBL16416836 | 0.83 | CTNNB1 (0.43) | CTNNB1WNT3APRKCICLK1DYRK1A | |
| SCHEMBL12569413 | 0.83 | TAAR1 (0.53) | CTNNB1WNT3APRKCICLK1DYRK1A | |
| SCHEMBL12447477 | 0.83 | CTNNB1 (0.46) | CTNNB1WNT3APRKCICLK1DYRK1A | |
| Hydrochloric Acid SCHEMBL20562122 | 0.82 | TAAR1 (0.51) | CTNNB1WNT3APRKCICLK1DYRK1A | |
| SCHEMBL9112990 | 0.81 | CTNNB1 (0.43) | CTNNB1WNT3APRKCICLK1DYRK1A | |
| SCHEMBL80222 | 0.80 | PRKCI (0.46) | PRKCIPOLBALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8664264-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2014-03-04 | — | — | US | disclosed |
| US-20120251616-A1 | Tocopherols, Tocotrienols, Other Chroman and Side Chain Derivatives and Uses Thereof | SANDERS BOB G (US) | 2012-10-04 | — | — | US | disclosed |
| US-8148424-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-20100303899-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | SANDERS BOB G | 2010-12-02 | — | — | US | disclosed |
| US-7718814-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2010-05-18 | — | — | US | disclosed |
| EP-1115398-B1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RES DEV FOUNDATION (US) | 2010-05-05 | — | — | EP | disclosed |
| US-7608638-B2 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION (US) | 2009-10-27 | — | — | US | disclosed |
| US-20080161349-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2008-07-03 | — | — | US | disclosed |
| US-20080119514-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | SANDERS BOB G | 2008-05-22 | — | — | US | disclosed |
| EP-1254130-B1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RES DEV FOUNDATION (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2003039461-A2 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2003-05-15 | — | — | WO | disclosed |
| EP-1254130-A4 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RES DEV FOUNDATION (US) | 2003-04-23 | — | — | EP | disclosed |
| EP-1254130-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2002-11-06 | — | — | EP | disclosed |
| US-20020156024-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION | 2002-10-24 | — | — | US | disclosed |
| EP-1115398-A4 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RES DEV FOUNDATION (US) | 2002-10-16 | — | — | EP | disclosed |
| US-20020107207-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | RESEARCH DEVELOPMENT FOUNDATION | 2002-08-08 | — | — | US | disclosed |
| US-6417223-B1 | ANTIPROLIFERATION AGENTS OR APOTOPSIS | RESEARCH DEVELOPMENT FOUNDATION | 2002-07-09 | — | — | US | disclosed |
| WO-2001058889-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2001-08-16 | — | — | WO | disclosed |
| EP-1115398-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000016772-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | RESEARCH DEVELOPMENT FOUNDATION (US) | 2000-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100303899-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | TST, TXNRD3, TXNRD1 | CTNNB1 3518/4885WNT3A 3986/4885PRKCI 4514/4885 |
| US-20020156024-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | HCCS, TTPA, TST | CTNNB1 3070/4885WNT3A 3992/4885PRKCI 4403/4885 |
| US-20020107207-A1 | Tocopherols, tocotrienols, other chroman and side chain derivatives and uses thereof | TST, HCCS, TXNRD3 | CTNNB1 3078/4885WNT3A 3961/4885PRKCI 4466/4885 |
| US-20080161349-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | TST, TXNRD3, TXNRD1 | CTNNB1 3488/4885WNT3A 4031/4885PRKCI 4510/4885 |
| US-20080119514-A1 | TOCOPHEROLS, TOCOTRIENOLS, OTHER CHROMAN AND SIDE CHAIN DERIVATIVES AND USES THEREOF | TXN, TXN2, TTPA | CTNNB1 786/4885WNT3A 2311/4885PRKCI 4027/4885 |
| US-20120251616-A1 | Tocopherols, Tocotrienols, Other Chroman and Side Chain Derivatives and Uses Thereof | TST, TXNRD3, TXNRD1 | CTNNB1 3518/4885WNT3A 3986/4885PRKCI 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.