Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HK1 | P19367 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28670216 | 0.82 | TDP1 (0.39) | IDO1LMNAMAPTL3MBTL1SRC | |
| SCHEMBL624417 | 0.73 | CYP1A2 (0.41) | IDO1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL30518953 | 0.71 | DRD2 (0.38) | ALDH1A1KDM4EMEN1LMNAKMT2A | |
| SCHEMBL19873102 | 0.69 | IDO1 (0.41) | IDO1ABCG2ALDH1A1KDM4EMEN1 | |
| SCHEMBL28146373 | 0.69 | IDO1 (0.49) | IDO1ABCG2ALDH1A1KDM4EMEN1 | |
| SCHEMBL11300879 | 0.69 | IDO1 (0.37) | IDO1ABCG2ALDH1A1KDM4EMEN1 | |
| SCHEMBL12274879 | 0.68 | CDK2 (0.48) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29153463 | 0.68 | PLK1 (0.33) | IDO1ALDH1A1KDM4EMEN1APAF1 | |
| SCHEMBL2233984 | 0.68 | MAPT (0.38) | IDO1ABCG2ALDH1A1KDM4EMEN1 | |
| SCHEMBL4515365 | 0.67 | IDO1 (0.54) | IDO1ABCG2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1437122-B1 | Composition for dyeing keratinic fibers comprising diheteroarylmethane direct dye and dyeing process using this composition | OREAL (FR) | 2010-03-03 | — | — | EP | claimed |
| US-7217297-B2 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-15 | — | — | US | claimed |
| US-7211118-B2 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-01 | — | — | US | claimed |
| US-20040194231-A1 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | claimed |
| US-20040187229-A1 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-09-30 | — | — | US | claimed |
| EP-1437122-A1 | Composition for dyeing keratinic fibers comprising a diheteroarylmethane direct dye or its lecuco precursor and dyeing process using this composition | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| US-12396938-B2 | Compositions and methods for coloring hair | L'OREAL (FR) | 2025-08-26 | — | — | US | disclosed |
| EP-4580592-A1 | HAIR COLORING COMPOSITIONS | L'OREAL (FR) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050469-A1 | HAIR COLORING COMPOSITIONS | L'OREAL (FR) | 2024-03-07 | — | — | WO | disclosed |
| US-20240065956-A1 | COMPOSITIONS AND METHODS FOR COLORING HAIR | L'OREAL (FR) | 2024-02-29 | — | — | US | disclosed |
| US-11185485-B2 | Hair coloring compositions and methods of using the same | L'OREAL (FR) | 2021-11-30 | — | — | US | disclosed |
| US-20200375865-A1 | HAIR COLORING COMPOSITIONS AND METHODS OF USING THE SAME | L'OREAL (FR) | 2020-12-03 | — | — | US | disclosed |
| EP-2315615-B1 | METHODS AND KITS FOR PERMANENTLY COLORING HAIR USING PERSULFATES, PERBORATES OR PERCARBONATES | OREAL (FR) | 2019-11-20 | — | — | EP | disclosed |
| US-20090074701-A1 | METHODS OF ARTIFICIALLY COLORING HAIR | L'OREAL S.A. (FR) | 2009-03-19 | — | — | US | disclosed |
| US-20090074702-A1 | applying to an artificially-colored haira formulation comprising siloxysilicate resin and hexamethylene undecanamide (nylon 6,11/dimethicone copolymer, forms a film on the hair which fixes the artificial colorant to the hair | L'OREAL S.A. (FR) | 2009-03-19 | — | — | US | disclosed |
| US-7217297-B2 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-15 | — | — | US | disclosed |
| US-7211118-B2 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-01 | — | — | US | disclosed |
| US-20040194231-A1 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-10-07 | — | — | US | disclosed |
| US-20040187229-A1 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-09-30 | — | — | US | disclosed |
| EP-1437122-A1 | Composition for dyeing keratinic fibers comprising a diheteroarylmethane direct dye or its lecuco precursor and dyeing process using this composition | L'OREAL (FR) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200375865-A1 | HAIR COLORING COMPOSITIONS AND METHODS OF USING THE SAME | PHOSPHO1, SGMS1, DEGS1 | IDO1 68/4885ABCG2 1387/4885ALDH1A1 1398/4885 |
| US-20040194231-A1 | Composition for dyeing keratin fibers comprising a defined triheteroylmethane direct dye or leuco precursor of this dye and dyeing method using it | KRT18, KMO, KRTCAP2 | IDO1 1763/4885ABCG2 3855/4885ALDH1A1 2232/4885 |
| US-11185485-B2 | Hair coloring compositions and methods of using the same | PHOSPHO1, SGMS1, DEGS1 | IDO1 68/4885ABCG2 1387/4885ALDH1A1 1398/4885 |
| US-20090074701-A1 | METHODS OF ARTIFICIALLY COLORING HAIR | HDAC10, RARA, PRDM7 | IDO1 1537/4885ABCG2 4569/4885ALDH1A1 584/4885 |
| US-20040187229-A1 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | KRT18, KMO, DLD | IDO1 1373/4885ABCG2 1889/4885ALDH1A1 1560/4885 |
| US-20090074702-A1 | applying to an artificially-colored haira formulation comprising siloxysilicate resin and hexamethylene undecanamide (nylon 6,11/dimethicone copolymer, forms a film on the hair which fixes the artificial colorant to the hair | KRT18, CUTA, KDM6A | IDO1 3208/4885ABCG2 4486/4885ALDH1A1 2651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.