Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.52 |
| ▸ | ITGAL | P20701 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CRHBP | P24387 | 2/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4308991 | 0.78 | ABCG2 (0.44) | NOTUMPDK1ITGB2ICAM1ITGAL | |
| SCHEMBL15718087 | 0.75 | ITGB2 (0.52) | NOTUMPDK1ITGB2ICAM1ITGAL | |
| SCHEMBL17226696 | 0.75 | ITGB2 (0.52) | NOTUMPDK1ITGB2ICAM1ITGAL | |
| SCHEMBL29598502 | 0.75 | NOTUM (0.56) | NOTUMPDK1ITGB2ICAM1ITGAL | |
| SCHEMBL360572 | 0.75 | ITGB2 (0.52) | NOTUMPDK1ITGB2ICAM1ITGAL | |
| SCHEMBL18026809 | 0.75 | ITGB2 (0.52) | NOTUMPDK1ITGB2ICAM1ITGAL | |
| SCHEMBL6114033 | 0.75 | ITGB2 (0.52) | NOTUMPDK1ITGB2ICAM1ITGAL | |
| SCHEMBL519320 | 0.75 | NOTUM (0.56) | NOTUMPDK1ITGB2ICAM1ITGAL | |
| SCHEMBL26103119 | 0.75 | ITGB2 (0.52) | NOTUMPDK1ITGB2ICAM1ITGAL | |
| SCHEMBL3314700 | 0.75 | ITGB2 (0.52) | NOTUMPDK1ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260144724-A1 | Mixture of at least five surfactants (I1) to (I5) | WELLA GERMANY GMBH (DE) | 2026-05-28 | — | — | US | claimed |
| WO-2026104266-A1 | USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION | WELLA GERMANY GMBH (DE) | 2026-05-21 | — | — | WO | claimed |
| EP-4731170-A1 | OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE | Wella Germany GmbH (DE) | 2026-04-29 | — | — | EP | claimed |
| US-12564545-B2 | Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents | WELLA GERMANY GMBH (DE) | 2026-03-03 | — | — | US | claimed |
| CN-115980205-B | Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dye product | 江苏省食品药品监督检验研究院 | 2025-04-22 | — | — | CN | claimed |
| WO-2025031867-A1 | OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE | WELLA GERMANY GMBH (DE) | 2025-02-13 | — | — | WO | claimed |
| US-12109289-B2 | Compositions for imparting color and tone to the hair | L'OREAL (FR) | 2024-10-08 | — | — | US | claimed |
| US-11819562-B2 | Composition for dyeing keratin fibres and use thereof | L'OREAL (FR) | 2023-11-21 | — | — | US | claimed |
| CN-115980205-A | Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dyeing product | 江苏省食品药品监督检验研究院 | 2023-04-18 | — | — | CN | claimed |
| WO-2023017035-A1 | HAIR COLORING COMPOSITIONS COMPRISING HYDROXYALKYL AMINES AS ALKALISING AGENTS | WELLA GERMANY GMBH (DE) | 2023-02-16 | — | — | WO | claimed |
| US-8523956-B2 | Colouring composition for keratin fibres | KAO GERMANY GMBH (DE) | 2013-09-03 | — | — | US | claimed |
| WO-2013078492-A2 | AGENT AND METHOD FOR COLOURING KERATIN FIBRES | GW COSMETICS GMBH (AT) | 2013-06-06 | — | — | WO | claimed |
| EP-2547315-A1 | COLOURING COMPOSITION FOR KERATIN FIBRES | Kao Germany GmbH (DE) | 2013-01-23 | — | — | EP | claimed |
| US-20130000056-A1 | COLOURING COMPOSITION FOR KERATIN FIBRES | KAO GERMANY GMBH (DE) | 2013-01-03 | — | — | US | claimed |
| WO-2011113452-A1 | COLOURING COMPOSITION FOR KERATIN FIBRES | KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) | 2011-09-22 | — | — | WO | claimed |
| EP-2226065-A2 | Colouring composition for keratin fibres | KPSS-Kao Professional Salon Services GmbH (DE) | 2010-09-08 | — | — | EP | claimed |
| WO-2008099332-A1 | MULTISTEP HAIR COLOR REVITALIZING KIT AND ASSOCIATED METHODS | THE PROCTER & GAMBLE COMPANY (US) | 2008-08-21 | — | — | WO | claimed |
| US-20080189876-A1 | Multistep hair color revitalizing kit and associated methods | PROCTER & GAMBLE COMPANY, THE | 2008-08-14 | — | — | US | claimed |
| WO-2007048473-A1 | HAIR COLOURING AND/OR LIGHTENING METHOD WITH IMPROVED EFFICIENCY ACHIEVED BY UV LIGHT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-05-03 | — | — | WO | claimed |
| US-5447716-A | Topical application as lotion, cream, milk, gel, microspheres, dispersion | L'OREAL (FR) | 1995-09-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12564545-B2 | Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents | PHOSPHO1, ALDH7A1, AASDHPPT | NOTUM 4306/4885PDK1 2319/4885ITGB2 260/4885 |
| US-11819562-B2 | Composition for dyeing keratin fibres and use thereof | KRT18, KLK5, JUP | NOTUM 2699/4885PDK1 1711/4885ITGB2 1355/4885 |
| US-20260144724-A1 | Mixture of at least five surfactants (I1) to (I5) | DEGS1, SGMS1, FABP4 | NOTUM 350/4885PDK1 970/4885ITGB2 3538/4885 |
| US-12109289-B2 | Compositions for imparting color and tone to the hair | TYR, INMT, AADAT | NOTUM 2867/4885PDK1 1803/4885ITGB2 4787/4885 |
| US-20130000056-A1 | COLOURING COMPOSITION FOR KERATIN FIBRES | KRT18, MDN1, CUTA | NOTUM 1628/4885PDK1 1229/4885ITGB2 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.