SCHEMBL21470359

SCHEMBL21470359

O=C(OCc1ccc(Cl)cc1Cl)C1=C(c2ccccc2)C(=O)c2ccccc2C1=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.48
HSP90AA1 P07900 5/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
ALDH1A1 P00352 3/20 0.47
LMNA P02545 3/20 0.47
HKDC1 Q2TB90 3/20 0.47
NPSR1 Q6W5P4 3/20 0.47
KDM4E B2RXH2 3/20 0.47
MAPT P10636 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
PKM P14618 1/20 0.47
CYP2C19 P33261 1/20 0.47
NPC1 O15118 1/20 0.47
TP53 P04637 1/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21470361 0.83 ALDH1A1 (0.54) L3MBTL1HSP90AA1MEN1KMT2AALDH1A1
SCHEMBL445362 0.79 ALDH1A1 (0.56) L3MBTL1HSP90AA1MEN1KMT2AALDH1A1
SCHEMBL8340214 0.79 MAPT (0.56) L3MBTL1HSP90AA1MEN1KMT2AALDH1A1
SCHEMBL6666901 0.76 L3MBTL1 (0.74) L3MBTL1MEN1KMT2ALMNAMAPT
SCHEMBL13561203 0.75 HSP90AA1 (0.74) L3MBTL1HSP90AA1MEN1KMT2AALDH1A1
SCHEMBL17969781 0.74 ALDH1A1 (0.78) L3MBTL1HSP90AA1MEN1KMT2AALDH1A1
SCHEMBL21470357 0.73 MAPT (0.57) L3MBTL1HSP90AA1MEN1KMT2AALDH1A1
SCHEMBL15827661 0.73 NPSR1 (0.56) L3MBTL1HSP90AA1MEN1KMT2AALDH1A1
SCHEMBL13679127 0.73 NPSR1 (0.56) L3MBTL1HSP90AA1MEN1KMT2AALDH1A1
SCHEMBL147378 0.70 FGFR1 (0.72) HSP90AA1MAPTTP53FGFR1FGFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10656543-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-05-19 US disclosed
US-20190317414-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-10-17 US disclosed