Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30905945 | 0.88 | RAPGEF4 (0.39) | ENPP2CYP3A4TSHRHTR2BCHRM1 | |
| SCHEMBL29955565 | 0.86 | ALDH1A1 (0.38) | ENPP2CYP3A4TSHRHTR2BCHRM1 | |
| SCHEMBL13494614 | 0.86 | ALDH1A1 (0.38) | ENPP2CYP3A4TSHRHTR2BCHRM1 | |
| SCHEMBL448143 | 0.78 | CA2 (0.43) | TSHRCA2LPLLIPGRAPGEF4 | |
| SCHEMBL13084437 | 0.76 | CYP3A4 (0.48) | ENPP2CYP3A4HTR2BCHRM1ALOX15 | |
| SCHEMBL624402 | 0.75 | CYP3A4 (0.43) | ENPP2CYP3A4NOX1TSHRHTR2B | |
| SCHEMBL29825793 | 0.75 | CYP3A4 (0.43) | ENPP2CYP3A4NOX1TSHRHTR2B | |
| SCHEMBL21459591 | 0.74 | ACHE (0.39) | CA2LPLLIPGRAPGEF4ALOX5 | |
| SCHEMBL28836922 | 0.74 | CA2 (0.35) | ENPP2CA2LPLLIPG | |
| SCHEMBL3656240 | 0.74 | CA2 (0.40) | CYP3A4TSHRCA2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698517-A1 | <SUP2/>? <SUB2/>?4?NOVEL COMPOUNDS AS ?? <NS1:SUB>7</NS1:SUB>?INHIBITORS | Evotec International GmbH (DE) | 2026-02-25 | — | — | EP | disclosed |
| US-20250026766-A1 | Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors | BEIGENE, LTD. (KY) | 2025-01-23 | — | — | US | disclosed |
| EP-4463456-A1 | THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | BeiGene, Ltd. (KY) | 2024-11-20 | — | — | EP | disclosed |
| WO-2024218058-A1 | NOVEL COMPOUNDS AS α4β7 INHIBITORS | EVOTEC INTERNATIONAL GMBH (DE) | 2024-10-24 | — | — | WO | disclosed |
| CN-118510778-A | Thiazolopyridylamide derivatives as inhibitors of DNA polymerase θ | 百济神州有限公司 | 2024-08-16 | — | — | CN | disclosed |
| WO-2023134708-A1 | THIAZOLOPYRIDYL AMIDE DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | BEIGENE , LTD. (KY) | 2023-07-20 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| WO-2020130664-A1 | ORGANIC LUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DIODE USING SAME | 두산솔루스 주식회사 | 2020-06-25 | — | — | WO | disclosed |
| WO-2020130664-A1 | ORGANIC LUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DIODE USING SAME | 두산솔루스 주식회사 | 2020-06-25 | — | — | WO | disclosed |
| US-10160745-B2 | Piperidine and azepine derivatives as prokineticin receptor modulators | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-12-25 | — | — | US | disclosed |
| US-8507688-B2 | Process for preparing aryl- and heteroarylacetic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2013-08-13 | — | — | US | disclosed |
| WO-2011089072-A1 | METHOD FOR PRODUCING ARYL AND HETEROARYLACETIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | WO | disclosed |
| US-20110184180-A1 | Process for Preparing Aryl- and Heteroarylacetic Acid Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-07-28 | — | — | US | disclosed |
| US-7754103-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2010-07-13 | — | — | US | disclosed |
| US-7732021-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-06-08 | — | — | US | disclosed |
| US-7635505-B2 | Liquid Crystalline Medium | MERCK PATENT GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| US-20090194738-A1 | Liquid-crystalline medium | MANABE ATSUTAKA | 2009-08-06 | — | — | US | disclosed |
| US-20080277623-A1 | Liquid Crystalline Medium | MERCK PATENT GMBH (DE) | 2008-11-13 | — | — | US | disclosed |
| US-20080128653-A1 | Liquid Crystalline Medium | MERCK PATENT GMBH (DE) | 2008-06-05 | — | — | US | disclosed |
| US-20070135497-A1 | Biphenyl derivative or its salt, and pesticide containing it as an active ingredient | ISHIHARA SANGYO KAISHA LTD. (JP) | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080277623-A1 | Liquid Crystalline Medium | CHRM1, NEFM, CCNT1 | ENPP2 2276/4885CYP3A4 2777/4885NOX1 2365/4885 |
| US-10160745-B2 | Piperidine and azepine derivatives as prokineticin receptor modulators | GIPR, PROKR1, PROKR2 | ENPP2 1696/4885CYP3A4 1968/4885NOX1 4820/4885 |
| US-20110184180-A1 | Process for Preparing Aryl- and Heteroarylacetic Acid Derivatives | DDC, DDT, PAH | ENPP2 1382/4885CYP3A4 84/4885NOX1 4026/4885 |
| US-20250026766-A1 | Thiazolopyridyl Amide Derivatives as DNA Polymerase Theta Inhibitors | POLQ, POLK, POLI | ENPP2 3159/4885CYP3A4 1564/4885NOX1 2750/4885 |
| US-20070135497-A1 | Biphenyl derivative or its salt, and pesticide containing it as an active ingredient | DDT, HCN1, HCN2 | ENPP2 1978/4885CYP3A4 2206/4885NOX1 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.