Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21759614 | 0.91 | MAPT (0.41) | NPC1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL28879176 | 0.83 | ALDH1A1 (0.49) | NPC1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL28772850 | 0.82 | NPC1 (0.46) | NPC1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL14960825 | 0.73 | DPP4 (0.47) | NPC1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL499141 | 0.73 | ALDH1A1 (0.53) | NPC1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL28154232 | 0.72 | NPC1 (0.49) | NPC1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL28464758 | 0.71 | PDE5A (0.49) | NPC1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL27110794 | 0.71 | KDM4E (0.50) | NPC1SMN1; SMN2MAPTALDH1A1KDM4E | |
| SCHEMBL23008430 | 0.71 | NPC1 (0.52) | NPC1SMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL13719392 | 0.71 | NPC1 (0.52) | NPC1SMN1; SMN2MAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11672174-B2 | Pyrene-triazine derivative and applications thereof in organic electronic component | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2023-06-06 | — | — | US | disclosed |
| US-11239428-B2 | Boron-containing organic compound and applications thereof, organic mixture, and organic electronic device | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2022-02-01 | — | — | US | disclosed |
| US-20190334093-A1 | PYRENE-TRIAZINE DERIVATIVE AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC COMPONENT | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-10-31 | — | — | US | disclosed |
| US-20190319197-A1 | ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE | GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) | 2019-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190334093-A1 | PYRENE-TRIAZINE DERIVATIVE AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC COMPONENT | TPR, TRPC5, TRPC4 | NPC1 1367/4885SMN1; SMN2 3504/4885MAPT 509/4885 |
| US-11672174-B2 | Pyrene-triazine derivative and applications thereof in organic electronic component | TPR, TRPC5, TRPC4 | NPC1 1367/4885SMN1; SMN2 3504/4885MAPT 509/4885 |
| US-11239428-B2 | Boron-containing organic compound and applications thereof, organic mixture, and organic electronic device | BCL6B, BCL6, BTD | NPC1 618/4885SMN1; SMN2 2410/4885MAPT 1188/4885 |
| US-20190319197-A1 | ORGANIC COMPOUND, APPLICATIONS THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE | PIEZO1, OR10J3, OR51E2 | NPC1 856/4885SMN1; SMN2 3752/4885MAPT 2450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.