SCHEMBL21759614

SCHEMBL21759614

c1ccc(-c2ncnc(-c3cccc(-c4ccc(-c5cccs5)o4)c3)n2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.41
MEN1 O00255 6/20 0.41
KMT2A Q03164 6/20 0.41
KDM4E B2RXH2 5/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
LMNA P02545 1/20 0.41
POLB P06746 1/20 0.41
RECQL P46063 1/20 0.41
MCL1 Q07820 1/20 0.41
ALDH1A1 P00352 5/20 0.39
HSD17B10 Q99714 3/20 0.39
HPGD P15428 3/20 0.39
CACNA1B Q00975 1/20 0.39
APBA1 Q02410 1/20 0.39
NPSR1 Q6W5P4 2/20 0.38
PLA2G1B P04054 1/20 0.38
BLM P54132 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
NPC1 O15118 6/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21481189 0.91 NPC1 (0.42) MAPTMEN1KMT2AKDM4ETDP1
SCHEMBL28772850 0.79 NPC1 (0.46) MAPTMEN1KMT2AKDM4ETDP1
SCHEMBL28879176 0.77 ALDH1A1 (0.49) MAPTMEN1KMT2AKDM4ETDP1
SCHEMBL29693328 0.72 GP6 (0.47) MAPTMEN1KMT2AKDM4EL3MBTL1
SCHEMBL16922525 0.72 GP6 (0.47) MAPTMEN1KMT2AKDM4EL3MBTL1
SCHEMBL18134292 0.72 GP6 (0.47) MAPTMEN1KMT2AKDM4EL3MBTL1
SCHEMBL21881794 0.72 L3MBTL1 (0.48) MAPTMEN1KMT2AKDM4EL3MBTL1
SCHEMBL19512863 0.72 GP6 (0.47) MAPTMEN1KMT2AKDM4EL3MBTL1
SCHEMBL18134290 0.72 GP6 (0.47) MAPTMEN1KMT2AKDM4EL3MBTL1
SCHEMBL28467605 0.71 RAB9A (0.47) MAPTMEN1KMT2AKDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250112-A1 ORGANIC COMPOUNDS AND APPLICATIONS THEREOF IN OPTOELECTRONIC FIELD Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-08-10 US disclosed
US-11239428-B2 Boron-containing organic compound and applications thereof, organic mixture, and organic electronic device GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2022-02-01 US disclosed
US-20200066997-A1 ORGANIC COMPOUND CONTAINING BORON AND USES THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE GUANGZHOU CHINARAY OPTOELECTRONIC MATERIALS LTD. (CN) 2020-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250112-A1 ORGANIC COMPOUNDS AND APPLICATIONS THEREOF IN OPTOELECTRONIC FIELD AOX1, AOC2, OR10J3 MAPT 1093/4885MEN1 1783/4885KMT2A 4013/4885
US-20200066997-A1 ORGANIC COMPOUND CONTAINING BORON AND USES THEREOF, ORGANIC MIXTURE, AND ORGANIC ELECTRONIC DEVICE OR10J3, OSTC, BCL6B MAPT 1279/4885MEN1 552/4885KMT2A 2329/4885
US-11239428-B2 Boron-containing organic compound and applications thereof, organic mixture, and organic electronic device BCL6B, BCL6, BTD MAPT 1188/4885MEN1 630/4885KMT2A 2404/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.