Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 10/20 | 0.53 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.52 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.49 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21531580 | 0.90 | MEN1 (0.49) | GPR139SLC6A9TAOK1TAOK3NPC1 | |
| SCHEMBL9848834 | 0.89 | CTSK (0.52) | GPR139NPC1RAB9ASMN1; SMN2CTSS | |
| SCHEMBL21350190 | 0.84 | RIPK1 (0.52) | GPR139SLC6A9TAOK1TAOK3CTSS | |
| SCHEMBL19020179 | 0.84 | RIPK1 (0.52) | GPR139SLC6A9TAOK1TAOK3CTSS | |
| SCHEMBL18989461 | 0.83 | SMN1; SMN2 (0.48) | GPR139SLC6A9TAOK1TAOK3SMN1; SMN2 | |
| SCHEMBL18989460 | 0.83 | SMN1; SMN2 (0.48) | GPR139SLC6A9TAOK1TAOK3SMN1; SMN2 | |
| SCHEMBL21531711 | 0.82 | GPR139 (0.42) | GPR139 | |
| SCHEMBL5418894 | 0.82 | CTSS (0.48) | SLC6A9NPC1RAB9ASMN1; SMN2CTSS | |
| SCHEMBL9300286 | 0.80 | TSHR (0.54) | GPR139SLC6A9SLC6A5CTSSCTSK | |
| SCHEMBL15145801 | 0.79 | GPR139 (0.62) | GPR139CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190330141-A1 | Compositions With A Cooling Effect | THE PROCTER & GAMBLE COMPANY | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330141-A1 | Compositions With A Cooling Effect | CUTA, FABP4, EBP | GPR139 3261/4885SLC6A9 4716/4885TAOK1 3867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.