SCHEMBL21552083

SCHEMBL21552083

O=C(NCCCN1CCCCC1)c1ccc(/C=C/c2ccc(Cl)cc2Cl)cc1

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.55
F10 P00742 1/20 0.53
CACNA1G O43497 3/20 0.51
MAPT P10636 2/20 0.49
RECQL P46063 1/20 0.49
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
DRD2 P14416 1/20 0.48
DRD4 P21917 1/20 0.48
DRD3 P35462 1/20 0.48
TMEM97 Q5BJF2 1/20 0.48
SIGMAR1 Q99720 1/20 0.48
RAD52 P43351 1/20 0.48
HTR3A P46098 1/20 0.48
MCHR1 Q99705 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21552169 0.94 ALDH1A1 (0.63) ALDH1A1F10CACNA1GMEN1KMT2A
SCHEMBL21551981 0.91 LMNA (0.52) ALDH1A1MAPTMEN1KMT2ADRD2
SCHEMBL21551982 0.90 ALDH1A1 (0.59) ALDH1A1MEN1KMT2A
SCHEMBL21551989 0.88 ALDH1A1 (0.54) ALDH1A1F10CACNA1GMAPTRECQL
SCHEMBL21568402 0.84 ALDH1A1 (0.52) ALDH1A1MAPTMEN1KMT2ADRD2
SCHEMBL21552245 0.84 CD274 (0.68) ALDH1A1KMT2A
SCHEMBL21551964 0.82 TSHR (0.54) ALDH1A1MAPTRECQLKMT2ADRD2
SCHEMBL21568404 0.81 ALDH1A1 (0.49) ALDH1A1DRD2
SCHEMBL23599921 0.79 MEN1 (0.47) ALDH1A1F10CACNA1GMAPTRECQL
SCHEMBL21551990 0.78 LMNA (0.54) ALDH1A1MAPTMEN1KMT2ADRD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019216810-A1 NEW ANTIFUNGAL COMPOUNDS URBAN CONSTANTIN (SE) 2019-11-14 WO claimed
WO-2019216810-A1 NEW ANTIFUNGAL COMPOUNDS URBAN CONSTANTIN (SE) 2019-11-14 WO disclosed