Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21551990 | 0.91 | LMNA (0.54) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL21551944 | 0.90 | TSHR (0.59) | ALDH1A1LMNASMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL21552083 | 0.88 | ALDH1A1 (0.55) | ALDH1A1MAPTRECQLCACNA1GF10 | |
| SCHEMBL21551985 | 0.83 | CD274 (0.67) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL21552169 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CACNA1GF10CYP1A2CYP2D6 | |
| SCHEMBL23599921 | 0.79 | MEN1 (0.47) | ALDH1A1MAPTRECQLSMN1; SMN2CACNA1G | |
| SCHEMBL21551981 | 0.78 | LMNA (0.52) | ALDH1A1LMNAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL21551982 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL21551964 | 0.77 | TSHR (0.54) | ALDH1A1LMNAMAPTRECQLSMN1; SMN2 | |
| SCHEMBL5484126 | 0.77 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTRECQLCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | claimed |
| WO-2019216810-A1 | NEW ANTIFUNGAL COMPOUNDS | URBAN CONSTANTIN (SE) | 2019-11-14 | — | — | WO | disclosed |