SCHEMBL29355617

SCHEMBL29355617

C=C1C(=O)OC2C1CCC(C)C1CC(O)C(O)C12C

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ PAX8 Q06710 1/20 0.45
▸ PTGS2 P35354 4/20 0.44
▸ MAPT P10636 4/20 0.38
▸ RAB9A P51151 4/20 0.38
▸ NPC1 O15118 3/20 0.38
▸ XBP1 P17861 3/20 0.38
▸ HTT P42858 3/20 0.38
▸ MDM2 Q00987 3/20 0.38
▸ TERT O14746 1/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ GLA P06280 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ AGTR1 P30556 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ TDP1 Q9NUW8 1/20 0.35
▸ GPR55 Q9Y2T6 1/20 0.35
▸ PKM P14618 1/20 0.34
▸ RECQL P46063 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21563386 0.73 PAX8 (0.50) PAX8PTGS2MAPTRAB9ANPC1
Damsin SCHEMBL18642932 0.73 PTGS2 (0.55) PAX8PTGS2MAPTRAB9ANPC1
Damsin SCHEMBL18642934 0.73 PTGS2 (0.55) PAX8PTGS2MAPTRAB9ANPC1
SCHEMBL18550778 0.70 PAX8 (0.47) PAX8PTGS2MAPTRAB9ANPC1
SCHEMBL28044817 0.68 PTGS2 (0.59) PTGS2MAPTRAB9ANPC1XBP1
SCHEMBL31626700 0.68 PTGS2 (0.59) PTGS2MAPTRAB9ANPC1XBP1
Ambrosin SCHEMBL3463664 0.66 MAPT (0.54) PAX8PTGS2MAPTRAB9ANPC1
Ambrosin SCHEMBL3463663 0.66 MAPT (0.54) PAX8PTGS2MAPTRAB9ANPC1
SCHEMBL4067330 0.64 PAX8 (0.61) PAX8PTGS2MAPTRAB9APKM
Pseudoguaianolide SCHEMBL31387995 0.62 PTGS2 (0.55) PTGS2MAPTRAB9ANPC1XBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260103446-A1 CFTR REGULATORS AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2026-04-16 — — US disclosed
US-20260091043-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS DATA2DISCOVERY INC (US) 2026-04-02 — — US disclosed
EP-4382559-B1 BIOACTIVE NANOCOMPOSITE FILM OF THERMOPLASTIC STARCH, BACTERIAL CELLULOSE AND GALLIC ACID AND ITS USES RAIZ INSTITUTO DE INVESTIG DA FLORESTA E PAPEL (PT) 2026-02-18 — — EP disclosed
EP-4019501-B1 CFTR REGULATORS AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2026-02-04 — — EP disclosed
US-20250391228-A1 ANIMATING GAMING-TABLE OUTCOME INDICATORS FOR DETECTED RANDOMIZING-GAME-OBJECT STATES LNW GAMING INC (US) 2025-12-25 — — US disclosed
US-12503447-B2 CFTR regulators and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-23 — — US disclosed
US-12472054-B2 Inductive matrix for functional ocular surface reconstruction ALVARADO CARLOS A (GT) 2025-11-18 — — US disclosed
US-20250336256-A1 ENHANCED TRACKING OF GAME ELEMENTS AT A GAMING TABLE LNW GAMING, INC. 2025-10-30 — — US disclosed
US-20250336257-A1 PRE-EMPTIVELY MANAGING GAMING TABLE OUTCOMES LNW GAMING, INC. 2025-10-30 — — US disclosed
US-12391654-B2 CFTR regulators and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-08-19 — — US disclosed
WO-2022077007-A1 MOTIF NEOEPITOPES FOR CANCER IMMUNOTHERAPY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-14 — — WO disclosed
US-20220081402-A1 CFTR REGULATORS AND METHODS OF USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2022-03-17 — — US disclosed
CN-110015962-B Stilbene analogs and methods of treating cancer 肯塔基大学研究基金会 2022-03-15 — — CN disclosed
EP-3394046-B1 CFTR REGULATORS AND METHODS OF USE THEREOF UNIV CALIFORNIA (US) 2022-03-09 — — EP disclosed
CN-109476655-B Carbonic anhydrase IX-targeted nuclear imaging and radiotherapy agents and uses thereof 约翰霍普金斯大学 2022-03-08 — — CN disclosed
EP-3955869-A1 DEVICES AND METHODS FOR LASER SURGERY OF AN EYE, ESPECIALLY FOR KERATOPLASTY Carl Zeiss Meditec AG (DE) 2022-02-23 — — EP disclosed
WO-2022027035-A1 IN UTERO AND POSTNATAL GENE EDITING AND THERAPY FOR TREATMENT OF MONOGENIC DISEASES, INCLUDING MUCOPOLYSACCHARIDOSIS TYPE 1H AND OTHER DISORDERS THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2022-02-03 — — WO disclosed
WO-2022020097-A1 TRITURATION DEVICES FOR TISSUE DISAGGREGATION PRIM SIGMA TECHNOLOGIES (US) 2022-01-27 — — WO disclosed
US-20220025316-A1 TRITURATION DEVICES FOR TISSUE DISAGGREGATION PRIM SIGMA TECHNOLOGIES, INC. 2022-01-27 — — US disclosed
US-11230535-B2 CFTR regulators and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-01-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220081402-A1 CFTR REGULATORS AND METHODS OF USE THEREOF CFTR, SLC26A4, CLCN2 PAX8 2403/4885PTGS2 1280/4885MAPT 4825/4885
US-20260091043-A1 COMPOSITIONS AND METHODS FOR TREATING MYCOBACTERIUM INFECTIONS AHCY, MACO1, ME3 PAX8 4785/4885PTGS2 3699/4885MAPT 2120/4885
US-11230535-B2 CFTR regulators and methods of use thereof CFTR, SLC26A4, CLCN2 PAX8 2403/4885PTGS2 1280/4885MAPT 4825/4885
US-20250391228-A1 ANIMATING GAMING-TABLE OUTCOME INDICATORS FOR DETECTED RANDOMIZING-GAME-OBJECT STATES COG2, COG3, COG1 PAX8 1573/4885PTGS2 4007/4885MAPT 2267/4885
US-12391654-B2 CFTR regulators and methods of use thereof CFTR, SLC26A4, CLCN2 PAX8 2403/4885PTGS2 1280/4885MAPT 4825/4885
US-20260103446-A1 CFTR REGULATORS AND METHODS OF USE THEREOF CFTR, CLCN2, SLC26A3 PAX8 2434/4885PTGS2 1033/4885MAPT 4468/4885
US-12503447-B2 CFTR regulators and methods of use thereof CFTR, SLC26A4, CLCN2 PAX8 2403/4885PTGS2 1280/4885MAPT 4825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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