SCHEMBL10050880

SCHEMBL10050880

C=Cc1ccc(/C=N/CCNCC/N=C/c2ccc(/C=N/CCNCC(N)CCCCNC(=C)c3ccccc3)cc2)cc1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 2/20 0.32
GRIN2A Q12879 2/20 0.32
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215653 0.89 RAB9A (0.41) GRIN1GRIN2A
SCHEMBL13257066 0.79 GRIN1 (0.39) GRIN1GRIN2A
SCHEMBL216180 0.68 ALDH1A1 (0.38) TAAR1
SCHEMBL215253 0.65 HDAC1 (0.51) GRIN1GRIN2A
SCHEMBL18435782 0.65 HDAC1 (0.51) GRIN1GRIN2A
SCHEMBL10592837 0.63 CA2 (0.53) GRIN1GRIN2ATAAR1
SCHEMBL10592839 0.63 CA2 (0.53) GRIN1GRIN2ATAAR1
SCHEMBL14302995 0.62 TAS1R3 (0.44)
SCHEMBL11961215 0.62 CA2 (0.52) GRIN1GRIN2ATAAR1
SCHEMBL8760736 0.60 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8317999-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-11-27 US disclosed
US-8313639-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-11-20 US disclosed
US-8313625-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-11-20 US disclosed
US-8293082-B2 Methods and apparatus for measuring analytes using large scale FET arrays Life Technologies Corporation (US) 2012-10-23 US disclosed
US-20120071363-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2012-03-22 US disclosed
US-20110248319-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-10-13 US disclosed
US-20110247933-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-10-13 US disclosed
US-20110241081-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-10-06 US disclosed
US-20110230375-A1 METHODS AND APPARATUS FOR MEASURING ANALYTES USING LARGE SCALE FET ARRAYS Life Technologies Corporation (US) 2011-09-22 US disclosed
US-20090026082-A1 Methods and apparatus for measuring analytes using large scale FET arrays ION TORRENT SYSTEMS INCORPORATED (US) 2009-01-29 US disclosed