Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 1.00 |
| ▸ | TGM2 | P21980 | 6/20 | 0.73 |
| ▸ | MAOB | P27338 | 5/20 | 0.63 |
| ▸ | MAOA | P21397 | 4/20 | 0.63 |
| ▸ | CES1 | P23141 | 4/20 | 0.63 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.58 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 5-Methoxyisatin SCHEMBL29506298 | 1.00 | ALDH1A1 (1.00) | ALDH1A1TGM2MAOBMAOACES1 | |
| 5-Methoxyisatin SCHEMBL3935863 | 0.98 | ALDH1A1 (0.96) | ALDH1A1TGM2MAOBMAOACES1 | |
| 5-Methoxyisatin SCHEMBL28560213 | 0.92 | ALDH1A1 (0.84) | ALDH1A1TGM2MAOBMAOACES1 | |
| SCHEMBL1249793 | 0.85 | ALDH1A1 (0.74) | ALDH1A1TGM2MAOBMAOACES1 | |
| SCHEMBL1027756 | 0.85 | TGM2 (1.00) | ALDH1A1TGM2MAOBMAOACES1 | |
| SCHEMBL21179898 | 0.82 | ALDH1A1 (0.70) | ALDH1A1TGM2LRRK2PDE3BPDE3A | |
| SCHEMBL2372943 | 0.81 | ALDH1A1 (0.68) | ALDH1A1TGM2MAOBMAOACES1 | |
| SCHEMBL5918370 | 0.81 | ALDH1A1 (0.68) | ALDH1A1LRRK2PDE3BPDE3AMAPT | |
| SCHEMBL19928099 | 0.80 | ALDH1A1 (0.66) | ALDH1A1LRRK2PDE3BPDE3AMAPT | |
| SCHEMBL20246772 | 0.80 | ALDH1A1 (0.66) | ALDH1A1LRRK2PDE3BPDE3AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 938 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707805-A | Preparation method of 6-hydroxyquinoline-4-carboxylic acid | 上海德浦生物医药科技有限公司 | 2025-03-28 | — | — | CN | claimed |
| CN-119350241-A | Quinolinone derivative and preparation method and application thereof | 浙江工业大学 | 2025-01-24 | — | — | CN | claimed |
| CN-118852031-A | 2, 3-Disubstituted quinazolinone compound and preparation method thereof | 赣南师范大学 | 2024-10-29 | — | — | CN | claimed |
| CN-113912609-B | Preparation method of natural alkaloid tryptanthrin and derivatives thereof | 江苏大学 | 2024-01-05 | — | — | CN | claimed |
| US-11708373-B2 | 5-alkylquinazoline derivative, method of preparing the same, and method of using the same | HEFEI UNIVERSITY OF TECHNOLOGY (CN) | 2023-07-25 | — | — | US | claimed |
| CN-111187233-B | Polysubstituted benzothiazole and derivative and synthesis method thereof | 湘潭大学 | 2023-05-30 | — | — | CN | claimed |
| CN-114409684-B | Preparation and application of chiral amino zinc alkoxide complex | 合肥工业大学 | 2023-05-26 | — | — | CN | claimed |
| US-20220185819-A1 | 5-ALKYLQUINAZOLINE DERIVATIVE, METHOD OF PREPARING THE SAME, AND METHOD OF USING THE SAME | HEFEI UNIVERSITY OF TECHNOLOGY (CN) | 2022-06-16 | — | — | US | claimed |
| CN-114409684-A | Preparation and application of chiral amino zinc alkoxide complex | 合肥工业大学 | 2022-04-29 | — | — | CN | claimed |
| CN-112480126-B | Preparation and application of 5-alkyl quinazoline derivative | 合肥工业大学 | 2022-03-11 | — | — | CN | claimed |
| EP-1432388-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| EP-1432428-A1 | Agent for colouring fibres containing keratin | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| EP-1433469-A1 | Composition for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| WO-2004022016-A1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-03-18 | — | — | WO | claimed |
| US-6635090-B1 | Dyeing method using a specific cationic derivative and a compound selected among a specific aldehyde, a specific ketone, a quinone and a di-imino-isoindoline or 3-amino-isoindolone derivative | L'OREAL, S.A. (FR) | 2003-10-21 | — | — | US | claimed |
| WO-2003030847-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| WO-2003030842-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| US-6458168-B1 | Hair dyeing method using an aliphatic cationic amine and compound chosen from an aldehyde, a ketone, a quinone, a di-imino-isoindoline, and a 3-aminoisoindolone derivative | L'OREAL S.A. (FR) | 2002-10-01 | — | — | US | claimed |
| US-6451067-B1 | HAIR DYE MIXTURE | L'OREAL S.A. (FR) | 2002-09-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220185819-A1 | 5-ALKYLQUINAZOLINE DERIVATIVE, METHOD OF PREPARING THE SAME, AND METHOD OF USING THE SAME | MLN, PGA5, MCM5 | ALDH1A1 4145/4885TGM2 3481/4885MAOB 855/4885 |
| US-11708373-B2 | 5-alkylquinazoline derivative, method of preparing the same, and method of using the same | MLN, MCM5, PGA5 | ALDH1A1 3860/4885TGM2 3886/4885MAOB 1449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.