SCHEMBL2160767

SCHEMBL2160767

COc1ccc2s[c]nc2c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 6/20 0.43
NPC1 O15118 5/20 0.43
SMN1; SMN2 Q16637 4/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
NQO2 P16083 1/20 0.43
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
CYP3A4 P08684 1/20 0.41
DYRK1A Q13627 1/20 0.41
PPARA Q07869 4/20 0.40
PDK1 Q15118 1/20 0.40
BACE1 P56817 1/20 0.40
PDE3B Q13370 1/20 0.39
PDE3A Q14432 1/20 0.39
EGFR P00533 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5535853 0.86 KDR (0.43) RAB9ANPC1SMN1; SMN2KDM4EALDH1A1
SCHEMBL533470 0.85 CYP1A2 (0.49) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL482247 0.81 ALDH1A1 (0.45) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL18154124 0.77 NPC1 (0.45) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL5540744 0.76 ABL1 (0.44) RAB9ANPC1SMN1; SMN2KDM4EALDH1A1
SCHEMBL9007911 0.75 MTNR1A (0.38) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL1832902 0.75 MAPT (0.38) RAB9ANPC1SMN1; SMN2KDM4EALDH1A1
SCHEMBL7575561 0.73 NQO2 (0.39) SMN1; SMN2MEN1KMT2AKDM4EALDH1A1
SCHEMBL3048923 0.73 CA12 (0.46) RAB9ANPC1SMN1; SMN2MEN1KMT2A
SCHEMBL207013 0.71 DYRK1A (0.36) RAB9ANPC1SMN1; SMN2ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109997061-B Optical laminate, circularly polarizing plate, touch panel, and image display device 日本瑞翁株式会社 2022-07-15 CN claimed
CN-113307742-A Blue light absorption material, preparation method and application thereof, and blue light prevention lens 南京工业大学 2021-08-27 CN claimed
US-20060229335-A1 Diarylamine and arylheteroarylamine pyrazole derivatives as modulators of 5ht2a ARENA PHARMACEUTICALS, INC. 2006-10-12 US claimed
EP-1478634-A4 FURANONE DERIVATIVES GALILEO PHARMACEUTICALS INC (US) 2006-02-01 EP claimed
EP-1478634-A1 FURANONE DERIVATIVES Galileo Pharmaceuticals, Inc. (US) 2004-11-24 EP claimed
US-6667330-B2 Cytoprotective; neuroinflammation and neurodegenerative disorders; oxidative stress related conditions GALILEO PHARMACEUTICALS, INC. 2003-12-23 US claimed
US-20030176361-A1 Furanone derivatives MONSANTO TECHNOLOGY LLC 2003-09-18 US claimed
WO-2003064403-A1 FURANONE DERIVATIVES GALILEO LABORATORIES, INC. (US) 2003-08-07 WO claimed
US-4622178-A CEPHALOSPORIN INTERMEDIATES OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1986-11-11 US claimed
US-12038650-B2 Multilayer phase difference plate, polarizing plate, and image display device ZEON CORPORATION (JP) 2024-07-16 US disclosed
US-20240197682-A1 METHOD FOR TREATING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
US-20240201205-A1 METHOD FOR DETECTING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
WO-2024059845-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-21 WO disclosed
US-4116928-A Heterocylic ester, ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1978-09-26 US disclosed
US-4116929-A POLYESTERS EASTMAN KODAK COMPANY (US) 1978-09-26 US disclosed
US-4096115-A Ultraviolet light stabilized polymers EASTMAN KODAK COMPANY (US) 1978-06-20 US disclosed
US-4065427-A Polychromophoric heterocyclic ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1977-12-27 US disclosed
US-4017508-A POLYMERS EASTMAN KODAK COMPANY (US) 1977-04-12 US disclosed
US-4000148-A POLYMERS EASTMAN KODAK COMPANY (US) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS MAPT, HTT, PSEN1 RAB9A 2840/4885NPC1 256/4885SMN1; SMN2 9/4885
US-20030176361-A1 Furanone derivatives HSPA9, HSF1, IL1B RAB9A 2438/4885NPC1 1891/4885SMN1; SMN2 107/4885
US-12038650-B2 Multilayer phase difference plate, polarizing plate, and image display device RAD1, RPAP1, RPA1 RAB9A 1715/4885NPC1 3676/4885SMN1; SMN2 1172/4885
US-20060229335-A1 Diarylamine and arylheteroarylamine pyrazole derivatives as modulators of 5ht2a HTR2A, HTR5A, HTR2C RAB9A 853/4885NPC1 1750/4885SMN1; SMN2 2500/4885
US-20240197682-A1 METHOD FOR TREATING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS PRNP, PSEN1, SNCA RAB9A 3169/4885NPC1 1401/4885SMN1; SMN2 22/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.