SCHEMBL21624271

SCHEMBL21624271

O=c1c2ccc(O)c(O)c2sc2cccc(O)c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.42
MAOB P27338 1/20 0.42
CDK2 P24941 2/20 0.41
ATP1A1 P05023 3/20 0.41
ATP1B1 P05026 3/20 0.41
ATP1A3 P13637 3/20 0.41
ATP1B2 P14415 3/20 0.41
ATP1A2 P50993 3/20 0.41
ATP1B3 P54709 3/20 0.41
FXYD2 P54710 3/20 0.41
ATP1A4 Q13733 3/20 0.41
EGFR P00533 2/20 0.38
MAPT P10636 3/20 0.37
HPGD P15428 2/20 0.37
ALOX15 P16050 2/20 0.37
RECQL P46063 2/20 0.37
HSD17B10 Q99714 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
APP P05067 1/20 0.37
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30017741 1.00 MAOA (0.42) MAOAMAOBCDK2ATP1A1ATP1B1
SCHEMBL21624254 0.80 ALDH1A1 (0.53) MAOAMAOBATP1A1ATP1B1ATP1A3
SCHEMBL30017926 0.80 ALDH1A1 (0.53) MAOAMAOBATP1A1ATP1B1ATP1A3
SCHEMBL116182 0.76 MAOA (0.68) MAOAMAOBEGFRMAPTHPGD
SCHEMBL30161898 0.76 MAOA (0.68) MAOAMAOBEGFRMAPTHPGD
SCHEMBL31413531 0.76 MAOA (0.68) MAOAMAOBEGFRMAPTHPGD
SCHEMBL7361574 0.75 ATP1A1 (0.39) MAOAMAOBCDK2ATP1A1ATP1B1
SCHEMBL3877382 0.72 ALOX5 (0.54) MAOAMAOBMAPTHPGDALOX15
SCHEMBL5218956 0.71 MAOA (0.57) MAOAMAOBMAPTHPGDALOX15
SCHEMBL25782264 0.71 HPGD (0.48) MAOAMAOBCDK2EGFRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230082557-A1 Modified Thioxanthone Photoinitiators LINTFIELD LIMITED (GB) 2023-03-16 US claimed
CN-115279744-A Modified thioxanthone photoinitiators 林特弗德有限公司 2022-11-01 CN claimed
US-20210277017-A1 Thioxanthone Derivatives, Composition Comprising the Same and Pattern Forming Method Comprising Said Composition LINTFIELD LIMITED (GB) 2021-09-09 US claimed
CN-112969965-A Thioxanthone derivative, composition comprising the same, and pattern forming method comprising the composition 林特弗德有限公司 2021-06-15 CN claimed
US-12398152-B2 Thioxanthone derivatives, composition comprising the same and pattern forming method comprising said composition LINTFIELD LIMITED (GB) 2025-08-26 US disclosed
US-20210277017-A1 Thioxanthone Derivatives, Composition Comprising the Same and Pattern Forming Method Comprising Said Composition LINTFIELD LIMITED (GB) 2021-09-09 US disclosed
US-20210277017-A1 Thioxanthone Derivatives, Composition Comprising the Same and Pattern Forming Method Comprising Said Composition LINTFIELD LIMITED (GB) 2021-09-09 US disclosed
CN-112969965-A Thioxanthone derivative, composition comprising the same, and pattern forming method comprising the composition 林特弗德有限公司 2021-06-15 CN disclosed
EP-3824349-A1 THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION Lintfield Limited (GB) 2021-05-26 EP disclosed
WO-2020016389-A1 THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION LINTFIELD LIMITED (GB) 2020-01-23 WO disclosed
WO-2020016389-A1 THIOXANTHONE DERIVATIVES, COMPOSITION COMPRISING THE SAME AND PATTERN FORMING METHOD COMPRISING SAID COMPOSITION LINTFIELD LIMITED (GB) 2020-01-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230082557-A1 Modified Thioxanthone Photoinitiators TPMT, PPOX, TST MAOA 358/4885MAOB 469/4885CDK2 1780/4885
US-12398152-B2 Thioxanthone derivatives, composition comprising the same and pattern forming method comprising said composition TPMT, TST, PPOX MAOA 570/4885MAOB 712/4885CDK2 1871/4885
US-20210277017-A1 Thioxanthone Derivatives, Composition Comprising the Same and Pattern Forming Method Comprising Said Composition TPMT, TST, PPOX MAOA 570/4885MAOB 712/4885CDK2 1871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.