SCHEMBL21628513

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628798	0.92	LMNA (0.49)	IGFBP3LMNAMAPK1HTTRAB9A
	SCHEMBL21628455	0.91	LMNA (0.48)	IGFBP3LMNAMAPK1HTTRAB9A
	SCHEMBL21628817	0.89	LMNA (0.51)	IGFBP3LMNAMAPK1HTTRAB9A
	SCHEMBL21656739	0.89	IGFBP3 (0.59)	IGFBP3LMNAMAPK1HTTRAB9A
	SCHEMBL21628807	0.88	PARP10 (0.54)	IGFBP3KDM4EMAPTPARP10
	SCHEMBL21628770	0.85	ALDH1A1 (0.51)	IGFBP3LMNAMAPK1HTTRAB9A
	SCHEMBL21628839	0.85	OPRM1 (0.45)	IGFBP3MAPK1KDM4EMAPT
	SCHEMBL19357374	0.84	RAB9A (0.56)	IGFBP3LMNAMAPK1HTTRAB9A
	SCHEMBL21628649	0.84	HPGD (0.51)	IGFBP3MAPK1HTTKDM4EMAPT
	SCHEMBL21628846	0.84	SLC6A2 (0.53)	IGFBP3LMNAMAPK1HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.